FOXL1 Antibody - #AF0705

(1)  
製品: FOXL1 Antibody
カタログ: AF0705
タンパク質の説明: Rabbit polyclonal antibody to FOXL1
アプリケーション: WB IF/ICC
反応性: Human, Monkey
予測: Bovine, Sheep, Dog
分子量: 36kDa; 36kD(Calculated).
ユニプロット: Q12952
RRID: AB_2834248

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関連ダウンロード
MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Monkey
予測:
Bovine(82%), Sheep(82%), Dog(80%)
クローナリティ:
Polyclonal
特異性:
FOXL1 Antibody detects endogenous levels of total FOXL1.
RRID:
AB_2834248
引用形式: Affinity Biosciences Cat# AF0705, RRID:AB_2834248.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

FKH 6; FKH6; FKHL 11; FKHL11; Forkhead (Drosophila) like 11; Forkhead box L1; Forkhead box protein L1; Forkhead related protein FKHL11; Forkhead related transcription factor 7; Forkhead-related protein FKHL11; Forkhead-related transcription factor 7; FOX L1; FOXL 1; Foxl1; FOXL1_HUMAN; FREAC 7; FREAC-7; FREAC7;

免疫原

免疫原:

A synthesized peptide derived from human FOXL1, corresponding to a region within the internal amino acids.

Uniprot:

Q12952(FOXL1_HUMAN) >>Visit HPA database.

遺伝子(ID):
FOXL1(2300)
タンパク質の説明:
FOXL1 Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors.
タンパク質配列:
MSHLFDPRLPALAASPMLYLYGPERPGLPLAFAPAAALAASGRAETPQKPPYSYIALIAMAIQDAPEQRVTLNGIYQFIMDRFPFYHDNRQGWQNSIRHNLSLNDCFVKVPREKGRPGKGSYWTLDPRCLDMFENGNYRRRKRKPKPGPGAPEAKRPRAETHQRSAEAQPEAGSGAGGSGPAISRLQAAPAGPSPLLDGPSPPAPLHWPGTASPNEDAGDAAQGAAAVAVGQAARTGDGPGSPLRPASRSSPKSSDKSKSFSIDSILAGKQGQKPPSGDELLGGAKPGPGGRLGASLLAASSSLRPPFNASLMLDPHVQGGFYQLGIPFLSYFPLQVPDTVLHFQ

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
82
Sheep
82
Dog
80
Pig
78
Horse
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Transcription factor required for proper proliferation and differentiation in the gastrointestinal epithelium. Target gene of the hedgehog (Hh) signaling pathway via GLI2 AND GLI3 transcription factors (By similarity).

細胞の位置付け:

Nucleus.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location

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