MMP23 Antibody - #AF0216
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0216, RRID:AB_2833346.
折りたたみ／展開
Femalysin; Matrix metallopeptidase 21; Matrix metallopeptidase 23A (pseudogene); Matrix metallopeptidase 23A; Matrix metallopeptidase 23B; Matrix metalloproteinase 22; Matrix metalloproteinase 23; Matrix metalloproteinase 23B; Matrix metalloproteinase in the female reproductive tract; Matrix metalloproteinase-21; Matrix metalloproteinase-22; Matrix metalloproteinase-23; MIFR; MIFR-1; MIFR1; MMP 23; MMP-21; MMP-22; MMP-23; MMP21; MMP22; MMP23_HUMAN; MMP23A; MMP23B; soluble form;
免疫原
A synthesized peptide derived from human MMP23, corresponding to a region within C-terminal amino acids.
- O75900 MMP23_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGRGARVPSEAPGAGVERRWLGAALVALCLLPALVLLARLGAPAVPAWSAAQGDVAALGLSAVPPTRVPGPLAPRRRRYTLTPARLRWDHFNLTYRILSFPRNLLSPRETRRALAAAFRMWSDVSPFSFREVAPEQPSDLRIGFYPINHTDCLVSALHHCFDGPTGELAHAFFPPHGGIHFDDSEYWVLGPTRYSWKKGVWLTDLVHVAAHEIGHALGLMHSQHGRALMHLNATLRGWKALSQDELWGLHRLYGCLDRLFVCASWARRGFCDARRRLMKRLCPSSCDFCYEFPFPTVATTPPPPRTKTRLVPEGRNVTFRCGQKILHKKGKVYWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTCVVRRQQRVLTTYSWRVRVRG
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Protease. May regulate the surface expression of some potassium channels by retaining them in the endoplasmic reticulum (By similarity).
N-glycosylated.
Proteolytic cleavage might yield an active form.
Endoplasmic reticulum membrane>Single-pass type II membrane protein. Membrane>Single-pass type II membrane protein.
Note: A secreted form produced by proteolytic cleavage may also exist.
Predominantly expressed in ovary, testis and prostate.
The ShKT domain associates with, and blocks several potassium channels in the nanomolar to low micromolar range. The relative affinity is Kv1.6 > Kv1.3 > Kv1.1 = Kv3.2 > Kv1.4 (By similarity).
Belongs to the peptidase M10A family.
Restrictive clause
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