GPR1 Antibody - #DF2801

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製品: GPR1 Antibody
カタログ: DF2801
タンパク質の説明: Rabbit polyclonal antibody to GPR1
アプリケーション: ELISA(peptide)
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Dog, Chicken
分子量: 41 kDa(Observed); 41kD(Calculated).
ユニプロット: P46091
RRID: AB_2840007

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#DF2801-BP

GPR1 Peptide

1mg
関連ダウンロード
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
反応性:
Human, Mouse, Rat
予測:
Pig(88%), Bovine(%), Horse(%), Dog(%), Chicken(%)
クローナリティ:
Polyclonal
特異性:
GPR1 Antibody detects endogenous levels of total GPR1.
RRID:
AB_2840007
引用形式: Affinity Biosciences Cat# DF2801, RRID:AB_2840007.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

G protein coupled receptor 1; G-protein coupled receptor 1; GPR1; GPR1_HUMAN; Probable G protein coupled receptor 1;

免疫原

免疫原:

A synthesized peptide derived from human GPR1, corresponding to a region within C-terminal amino acids.

Uniprot:

P46091(GPR1_HUMAN) >>Visit HPA database.

遺伝子(ID):
GPR1(2825)
発現特異性:
P46091 GPR1_HUMAN:

Expressed in hippocampus.

タンパク質の説明:
Receptor for the inflammation-associated leukocyte chemoattractant chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation. Can act as a coreceptor for HIV-1.;
タンパク質配列:
MEDLEETLFEEFENYSYDLDYYSLESDLEEKVQLGVVHWVSLVLYCLAFVLGIPGNAIVIWFTGFKWKKTVTTLWFLNLAIADFIFLLFLPLYISYVAMNFHWPFGIWLCKANSFTAQLNMFASVFFLTVISLDHYIHLIHPVLSHRHRTLKNSLIVIIFIWLLASLIGGPALYFRDTVEFNNHTLCYNNFQKHDPDLTLIRHHVLTWVKFIIGYLFPLLTMSICYLCLIFKVKKRSILISSRHFWTILVVVVAFVVCWTPYHLFSIWELTIHHNSYSHHVMQAGIPLSTGLAFLNSCLNPILYVLISKKFQARFRSSVAEILKYTLWEVSCSGTVSEQLRNSETKNLCLLETAQ

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Dog
100
Chicken
100
Pig
88
Bovine
88
Sheep
75
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Receptor for the inflammation-associated leukocyte chemoattractant chemerin/RARRES2 suggesting a role for this receptor in the regulation of inflammation. Receptor for TAFA1, mediates its effects on neuronal stem-cell proliferation and differentiation via the activation of ROCK/ERK and ROCK/STAT3 signaling pathway (By similarity).

(Microbial infection) Coreceptor for HIV-1.

細胞の位置付け:

Cell membrane>Multi-pass membrane protein.
Note: Internalizes in presence of its ligand, TAFA1.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in hippocampus.

タンパク質ファミリー:

Belongs to the G-protein coupled receptor 1 family.

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