SLC35C2 Antibody - #DF2473
| 製品: | SLC35C2 Antibody |
| カタログ: | DF2473 |
| タンパク質の説明: | Rabbit polyclonal antibody to SLC35C2 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse |
| 分子量: | 40 kDa; 40kD(Calculated). |
| ユニプロット: | Q9NQQ7 |
| RRID: | AB_2839679 |
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF2473, RRID:AB_2839679.
折りたたみ／展開
BA394O2.1; C20orf5; CGI-15; FLJ37039; MGC20633; MGC32079; MGC39183; Ovarian cancer-overexpressed gene 1 protein; OVCOV1; S35C2_HUMAN; SLC35C2; Solute carrier family 35 (GDP fucose transporter), member C2; Solute carrier family 35 member C2;
免疫原
A synthesized peptide derived from human SLC35C2, corresponding to a region within C-terminal amino acids.
Ubiquitously expressed although the level of expression is tissue dependent. Overexpressed in ovarian cancer.
- Q9NQQ7 S35C2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGRWALDVAFLWKAVLTLGLVLLYYCFSIGITFYNKWLTKSFHFPLFMTMLHLAVIFLFSALSRALVQCSSHRARVVLSWADYLRRVAPTALATALDVGLSNWSFLYVTVSLYTMTKSSAVLFILIFSLIFKLEELRAALVLVVLLIAGGLFMFTYKSTQFNVEGFALVLGASFIGGIRWTLTQMLLQKAELGLQNPIDTMFHLQPLMFLGLFPLFAVFEGLHLSTSEKIFRFQDTGLLLRVLGSLFLGGILAFGLGFSEFLLVSRTSSLTLSIAGIFKEVCTLLLAAHLLGDQISLLNWLGFALCLSGISLHVALKALHSRGDGGPKALKGLGSSPDLELLLRSSQREEGDNEEEEYFVAQGQQ
研究背景
May play an important role in the cellular response to tissue hypoxia. May be either a GDP-fucose transporter that competes with SLC35C1 for GDP-fucose, or a factor that otherwise enhances the fucosylation of Notch and is required for optimal Notch signaling in mammalian cells.
Membrane>Multi-pass membrane protein. Golgi apparatus>cis-Golgi network membrane. Endoplasmic reticulum-Golgi intermediate compartment membrane.
Ubiquitously expressed although the level of expression is tissue dependent. Overexpressed in ovarian cancer.
Belongs to the TPT transporter family. SLC35C subfamily.
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