| 製品: | CENPO Antibody |
| カタログ: | DF2316 |
| タンパク質の説明: | Rabbit polyclonal antibody to CENPO |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse |
| 予測: | Pig |
| 分子量: | 34 kDa(Observed); 34kD(Calculated). |
| ユニプロット: | Q9BU64 |
| RRID: | AB_2839540 |
Control Products
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF2316, RRID:AB_2839540.
折りたたみ／展開
CENP-O; CENPO; CENPO_HUMAN; Centromere protein O; ICEN 36; Interphase centromere complex protein 36; MCM21R;
免疫原
A synthesized peptide derived from human CENPO, corresponding to a region within the internal amino acids.
- Q9BU64 CENPO_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MEQANPLRPDGESKGGVLAHLERLETQVSRSRKQSEELQSVQAQEGALGTKIHKLRRLRDELRAVVRHRRASVKACIANVEPNQTVEINEQEALEEKLENVKAILQAYHFTGLSGKLTSRGVCVCISTAFEGNLLDSYFVDLVIQKPLRIHHHSVPVFIPLEEIAAKYLQTNIQHFLFSLCEYLNAYSGRKYQADRLQSDFAALLTGPLQRNPLCNLLSFTYKLDPGGQSFPFCARLLYKDLTATLPTDVTVTCQGVEVLSTSWEEQRASHETLFCTKPLHQVFASFTRKGEKLDMSLVS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Component of the CENPA-CAD (nucleosome distal) complex, a complex recruited to centromeres which is involved in assembly of kinetochore proteins, mitotic progression and chromosome segregation. May be involved in incorporation of newly synthesized CENPA into centromeres via its interaction with the CENPA-NAC complex. Modulates the kinetochore-bound levels of NDC80 complex.
Nucleus. Chromosome>Centromere. Chromosome>Centromere>Kinetochore.
Note: The CENPA-CAD complex is probably recruited on centromeres by the CENPA-NAC complex.
Belongs to the CENP-O/MCM21 family.
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