SNRPE Antibody - #DF7370
| 製品: | SNRPE Antibody |
| カタログ: | DF7370 |
| タンパク質の説明: | Rabbit polyclonal antibody to SNRPE |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Zebrafish, Bovine, Chicken, Xenopus |
| 分子量: | 10kDa; 11kD(Calculated). |
| ユニプロット: | P62304 |
| RRID: | AB_2839308 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF7370, RRID:AB_2839308.
折りたたみ／展開
AL022645; B raf; B-raf; Braf; C76690; HYPT11; RUXE_HUMAN; Sm protein E; Sm-E; Small nuclear ribonucleoprotein E; SmE; snRNP-E; snRNPE; snrpe;
免疫原
A synthesized peptide derived from human SNRPE, corresponding to a region within the internal amino acids.
Widely expressed. In scalp skin, it is present in the hair follicle, the epidermis, and the dermis.
- P62304 RUXE_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAYRGQGQKVQKVMVQPINLIFRYLQNRSRIQVWLYEQVNMRIEGCIIGFDEYMNLVLDDAEEIHSKTKSRKQLGRIMLKGDNITLLQSVSN
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Plays role in pre-mRNA splicing as core component of the SMN-Sm complex that mediates spliceosomal snRNP assembly and as component of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Component of both the pre-catalytic spliceosome B complex and activated spliceosome C complexes. Is also a component of the minor U12 spliceosome. As part of the U7 snRNP it is involved in histone 3'-end processing. May indirectly play a role in hair development.
Cytoplasm>Cytosol. Nucleus.
Note: SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.
Widely expressed. In scalp skin, it is present in the hair follicle, the epidermis, and the dermis.
Belongs to the snRNP Sm proteins family.
研究領域
· Genetic Information Processing > Transcription > Spliceosome.
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