CD83 Antibody - #DF6774

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製品: CD83 Antibody
カタログ: DF6774
タンパク質の説明: Rabbit polyclonal antibody to CD83
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
分子量: 23kDa(Observed); 23kD(Calculated).
ユニプロット: Q01151
RRID: AB_2838736

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#DF6774-BP

CD83 Peptide

1mg
関連ダウンロード
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
CD83 Antibody detects endogenous levels of total CD83.
RRID:
AB_2838736
引用形式: Affinity Biosciences Cat# DF6774, RRID:AB_2838736.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

B cell activation 45kDa cell surface glycoprotein Ig superfamily; B cell activation protein; B-cell activation protein; BL11; BL11 PEN; CD83; CD83 antigen (activated B lymphocytes, immunoglobulin superfamily); CD83 antigen; CD83 molecule; CD83_HUMAN; Cell surface glycoprotein; Cell surface protein HB15; HB15; hCD83;

免疫原

免疫原:

A synthesized peptide derived from human CD83, corresponding to a region within the internal amino acids.

Uniprot:

Q01151(CD83_HUMAN) >>Visit HPA database.

遺伝子(ID):
CD83(9308)
発現特異性:
Q01151 CD83_HUMAN:

Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells.

タンパク質の説明:
The protein encoded by this gene is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The encoded protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
タンパク質配列:
MSRGLQLLLLSCAYSLAPATPEVKVACSEDVDLPCTAPWDPQVPYTVSWVKLLEGGEERMETPQEDHLRGQHYHQKGQNGSFDAPNERPYSLKIRNTTSCNSGTYRCTLQDPDGQRNLSGKVILRVTGCPAQRKEETFKKYRAEIVLLLALVIFYLTLIIFTCKFARLQSIFPDFSKAGMERAFLPVTSPNKHLGLVTPHKTELV

研究背景

機能:

May play a significant role in antigen presentation or the cellular interactions that follow lymphocyte activation.

細胞の位置付け:

Membrane>Single-pass type I membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed by activated lymphocytes, Langerhans cells and interdigitating reticulum cells.

参考文献

1). Paricalcitol promotes the maturation of immune granulomas in an experimental model of superoxide dismutase A-induced inflammation. Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2025 (PubMed: 40355595) [IF=4.8]
2). Иммуногистохимическая характеристика биопсийных образцов десны в области беззубого альвеолярного края челюсти. Пародонтология, 2024

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