CD38 Antibody - #DF6551
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製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF6551, RRID:AB_2838513.
折りたたみ／展開
Acute lymphoblastic leukemia cells antigen CD38; ADP ribosyl cyclase 1; ADP ribosyl cyclase; ADP ribosyl cyclase/cyclic ADP-ribose hydrolase; ADP-ribosyl cyclase 1; ADPRC 1; ADPRC1; cADPr hydrolase 1; CD 38; CD38; CD38 antigen (p45); CD38 antigen; CD38 molecule; Cd38-rs1; CD38_HUMAN; CD38H; Cyclic ADP ribose hydrolase; Cyclic ADP ribose hydrolase 1; Cyclic ADP-ribose hydrolase 1; EC 3.2.2.5; Ecto nicotinamide adenine dinucleotide glycohydrolase; I-19; I19 (mouse); Lymphocyte differentiation antigen CD38; NAD(+) nucleosidase; NIM-R5 antigen; NIMR5 antigen (mouse); OTTHUMP00000158633; OTTHUMP00000217743; p45; T10;
免疫原
Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
- P28907 CD38_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MANCEFSPVSGDKPCCRLSRRAQLCLGVSILVLILVVVLAVVVPRWRQQWSGPGTTKRFPETVLARCVKYTEIHPEMRHVDCQSVWDAFKGAFISKHPCNITEEDYQPLMKLGTQTVPCNKILLWSRIKDLAHQFTQVQRDMFTLEDTLLGYLADDLTWCGEFNTSKINYQSCPDWRKDCSNNPVSVFWKTVSRRFAEAACDVVHVMLNGSRSKIFDKNSTFGSVEVHNLQPEKVQTLEAWVIHGGREDSRDLCQDPTIKELESIISKRNIQFSCKNIYRPDKFLQCVKNPEDSSCTSEI
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P28907 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| K13 | Ubiquitination | Uniprot | |
| N100 | N-Glycosylation | Uniprot | |
| N209 | N-Glycosylation | Uniprot | |
| N219 | N-Glycosylation | Uniprot | |
| T258 | Phosphorylation | Uniprot |
研究背景
Synthesizes the second messengers cyclic ADP-ribose and nicotinate-adenine dinucleotide phosphate, the former a second messenger for glucose-induced insulin secretion. Also has cADPr hydrolase activity. Also moonlights as a receptor in cells of the immune system.
Membrane>Single-pass type II membrane protein.
Expressed at high levels in pancreas, liver, kidney, brain, testis, ovary, placenta, malignant lymphoma and neuroblastoma.
Belongs to the ADP-ribosyl cyclase family.
研究領域
· Environmental Information Processing > Signal transduction > Calcium signaling pathway. (View pathway)
· Human Diseases > Infectious diseases: Viral > Epstein-Barr virus infection.
· Metabolism > Metabolism of cofactors and vitamins > Nicotinate and nicotinamide metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
· Organismal Systems > Immune system > Hematopoietic cell lineage. (View pathway)
· Organismal Systems > Endocrine system > Oxytocin signaling pathway.
· Organismal Systems > Digestive system > Salivary secretion.
· Organismal Systems > Digestive system > Pancreatic secretion.
参考文献
Application: IHC Species: Human Sample:
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