LCN6 Antibody - #DF6336

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製品: LCN6 Antibody
カタログ: DF6336
タンパク質の説明: Rabbit polyclonal antibody to LCN6
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
分子量: 18kDa; 18kD(Calculated).
ユニプロット: P62502
RRID: AB_2838300

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MS Report
HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:2000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
クローナリティ:
Polyclonal
特異性:
LCN6 Antibody detects endogenous levels of total LCN6.
RRID:
AB_2838300
引用形式: Affinity Biosciences Cat# DF6336, RRID:AB_2838300.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Epididymal specific lipocalin 6; Epididymal specific lipocalin ELP16; Epididymal specific lipocalin LCN6; hLcn5; LCN5; Lipocalin 5; Lipocalin 6; MCG18768; UNQ643;

免疫原

免疫原:

A synthesized peptide derived from human LCN6, corresponding to a region within the internal amino acids.

Uniprot:

P62502(LCN6_HUMAN) >>Visit HPA database.

遺伝子(ID):
LCN6(158062)
発現特異性:
P62502 LCN6_HUMAN:

Predominantly expressed in epididymis.

タンパク質の説明:
The Lipocalin family is composed of structurally conserved hydrophobic ligand binding proteins and is represented in all major taxonomic groups from prokaryotes to primates. Members of the lipocalin family are characterized by several common molecular-recognition properties: the ability to bind a range of small hydrophobic molecules, binding to specific cell-surface receptors and the formation of complexes with soluble macromolecules. Lipocalin-6, also known as LCN5, hLcn5, UNQ643 or LCN6, is a 163 amino acid protein that is predominantly expressed in epididymis. Lipocalin-6 locatizes to the head and tail of spermatozoa, with the highest concentration on the post-acrosomal region of the head. Belonging to the calycin superfamily, Lipocalin-6 may play a role in sperm maturation. The gene encoding Lipocalin-6 maps to human chromosome 9, which houses over 900 genes and comprises nearly 4% of the human genome.
タンパク質配列:
MGGLLLAAFLALVSVPRAQAVWLGRLDPEQLLGPWYVLAVASREKGFAMEKDMKNVVGVVVTLTPENNLRTLSSQHGLGGCDQSVMDLIKRNSGWVFENPSIGVLELWVLATNFRDYAIIFTQLEFGDEPFNTVELYSLTETASQEAMGLFTKWSRSLGFLSQ

研究背景

機能:

May play a role in male fertility.

細胞の位置付け:

Secreted.
Note: Located on the head and tail of spermatozoa with the highest concentration on the post-acrosomal region of the head, where it appears aggregated into large patches.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Predominantly expressed in epididymis.

タンパク質ファミリー:

Belongs to the calycin superfamily. Lipocalin family.

Restrictive clause

 

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