SLC16A3 Antibody - #AF5253
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| 製品: | SLC16A3 Antibody |
| カタログ: | AF5253 |
| タンパク質の説明: | Rabbit polyclonal antibody to SLC16A3 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 47 kDa; 49kD(Calculated). |
| ユニプロット: | O15427 |
| RRID: | AB_2837739 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF5253, RRID:AB_2837739.
折りたたみ／展開
MCT 4; MCT3; MCT4; Monocarboxylate transporter 3; Monocarboxylate transporter 4; MOT4_HUMAN; SLC16A3; Solute carrier family 16 member 3;
免疫原
- O15427 MOT4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGGAVVDEGPTGVKAPDGGWGWAVLFGCFVITGFSYAFPKAVSVFFKELIQEFGIGYSDTAWISSILLAMLYGTGPLCSVCVNRFGCRPVMLVGGLFASLGMVAASFCRSIIQVYLTTGVITGLGLALNFQPSLIMLNRYFSKRRPMANGLAAAGSPVFLCALSPLGQLLQDRYGWRGGFLILGGLLLNCCVCAALMRPLVVTAQPGSGPPRPSRRLLDLSVFRDRGFVLYAVAASVMVLGLFVPPVFVVSYAKDLGVPDTKAAFLLTILGFIDIFARPAAGFVAGLGKVRPYSVYLFSFSMFFNGLADLAGSTAGDYGGLVVFCIFFGISYGMVGALQFEVLMAIVGTHKFSSAIGLVLLMEAVAVLVGPPSGGKLLDATHVYMYVFILAGAEVLTSSLILLLGNFFCIRKKPKEPQPEVAAAEEEKLHKPPADSGVDLREVEHFLKAEPEKNGEVVHTPETSV
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O15427 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S35 | Phosphorylation | Uniprot | |
| Y36 | Phosphorylation | Uniprot | |
| K254 | Sumoylation | Uniprot | |
| K262 | Sumoylation | Uniprot | |
| K415 | Ubiquitination | Uniprot | |
| K428 | Ubiquitination | Uniprot | |
| K431 | Ubiquitination | Uniprot | |
| S436 | Phosphorylation | Uniprot | |
| K448 | Sumoylation | Uniprot | |
| K448 | Ubiquitination | Uniprot | |
| K453 | Ubiquitination | Uniprot | |
| T460 | Phosphorylation | Uniprot | |
| T463 | Phosphorylation | Uniprot | |
| S464 | Phosphorylation | Uniprot |
研究背景
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity).
Cell membrane>Multi-pass membrane protein.
Highly expressed in skeletal muscle.
Belongs to the major facilitator superfamily. Monocarboxylate porter (TC 2.A.1.13) family.
研究領域
· Human Diseases > Cancers: Overview > Central carbon metabolism in cancer. (View pathway)
参考文献
Application: WB Species: human Sample: Beas-2B cells
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