製品: TAS2R39 Antibody
カタログ: DF5161
タンパク質の説明: Rabbit polyclonal antibody to TAS2R39
アプリケーション: WB IF/ICC
反応性: Human
予測: Sheep
分子量: 36 KD; 39kD(Calculated).
ユニプロット: P59534
RRID: AB_2837510

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Sheep(88%)
クローナリティ:
Polyclonal
特異性:
TAS2R39 Antibody detects endogenous levels of total TAS2R39.
RRID:
AB_2837510
引用形式: Affinity Biosciences Cat# DF5161, RRID:AB_2837510.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

T2R39; T2R39_HUMAN; T2R57; TAS2R39; Taste receptor type 2 member 39; Taste receptor type 2 member 57;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P59534 T2R39_HUMAN:

Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

タンパク質配列:
MLGRCFPPDTKEKQQLRMTKLCDPAESELSPFLITLILAVLLAEYLIGIIANGFIMAIHAAEWVQNKAVSTSGRILVFLSVSRIALQSLMMLEITISSTSLSFYSEDAVYYAFKISFIFLNFCSLWFAAWLSFFYFVKIANFSYPLFLKLRWRITGLIPWLLWLSVFISFSHSMFCINICTVYCNNSFPIHSSNSTKKTYLSEINVVGLAFFFNLGIVTPLIMFILTATLLILSLKRHTLHMGSNATGSNDPSMEAHMGAIKAISYFLILYIFNAVALFIYLSNMFDINSLWNNLCQIIMAAYPASHSILLIQDNPGLRRAWKRLQLRLHLYPKEWTL

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Sheep
88
Pig
75
Dog
75
Horse
0
Bovine
0
Xenopus
0
Zebrafish
0
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P59534 基板として

Site PTM Type Enzyme
S143 Phosphorylation

研究背景

機能:

Receptor that may play a role in the perception of bitterness and is gustducin-linked. May play a role in sensing the chemical composition of the gastrointestinal content. The activity of this receptor may stimulate alpha gustducin, mediate PLC-beta-2 activation and lead to the gating of TRPM5 (By similarity).

細胞の位置付け:

Membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells.

タンパク質ファミリー:

Belongs to the G-protein coupled receptor T2R family.

研究領域

· Organismal Systems > Sensory system > Taste transduction.

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