OLFML2A Antibody - #DF5039

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製品: OLFML2A Antibody
カタログ: DF5039
タンパク質の説明: Rabbit polyclonal antibody to OLFML2A
アプリケーション: IF/ICC
反応性: Human, Mouse
分子量: 73 KD(Observed); 73kD(Calculated).
ユニプロット: Q68BL7
RRID: AB_2837398

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#DF5039-BP

OLFML2A Peptide

1mg
関連ダウンロード
Antigen/Blocking Peptide MS Report
Antigen/Blocking Peptide HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human, Mouse
クローナリティ:
Polyclonal
特異性:
OLFML2A Antibody detects endogenous levels of total OLFML2A.
RRID:
AB_2837398
引用形式: Affinity Biosciences Cat# DF5039, RRID:AB_2837398.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

FLJ00237; Olfactomedin like 2A; Olfactomedin like protein 2A; OLM2A_HUMAN; Photomedin 1; PRO34319; UNQ9394/PRO34319;

免疫原

免疫原:

A synthesized peptide derived from human OLFML2A, corresponding to a region within the internal amino acids.

Uniprot:

Q68BL7(OLM2A_HUMAN) >>Visit HPA database.

遺伝子(ID):
OLFML2A(169611)
発現特異性:
Q68BL7 OLM2A_HUMAN:

In the kidney expressed only by podocytes, wherein they localize to major processes.

タンパク質配列:
MAAAALPPRPLLLLPLVLLLSGRPTRADSKVFGDLDQVRMTSEGSDCRCKCIMRPLSKDACSRVRSGRARVEDFYTVETVSSGTDCRCSCTAPPSSLNPCENEWKMEKLKKQAPELLKLQSMVDLLEGTLYSMDLMKVHAYVHKVASQMNTLEESIKANLSRENEVVKDSVRHLSEQLRHYENHSAIMLGIKKELSRLGLQLLQKDAAAAPATPATGTGSKAQDTARGKGKDISKYGSVQKSFADRGLPKPPKEKLLQVEKLRKESGKGSFLQPTAKPRALAQQQAVIRGFTYYKAGKQEVTEAVADNTLQGTSWLEQLPPKVEGRSNSAEPNSAEQDEAEPRSSERVDLASGTPTSIPATTTTATTTPTPTTSLLPTEPPSGPEVSSQGREASCEGTLRAVDPPVRHHSYGRHEGAWMKDPAARDDRIYVTNYYYGNSLVEFRNLENFKQGRWSNMYKLPYNWIGTGHVVYQGAFYYNRAFTKNIIKYDLRQRFVASWALLPDVVYEDTTPWKWRGHSDIDFAVDESGLWVIYPAVDDRDEAQPEVIVLSRLDPGDLSVHRETTWKTRLRRNSYGNCFLVCGILYAVDTYNQQEGQVAYAFDTHTGTDARPQLPFLNEHAYTTQIDYNPKERVLYAWDNGHQLTYTLHFVV

研究背景

PTMs:

May be cleaved at Lys-295 after secretion.

O-glycosylated but not N-glycosylated.

細胞の位置付け:

Secreted.
Note: Localizes to the podocyte major processes. Colocalized with the major process protein VIM throughout podocyte development.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

In the kidney expressed only by podocytes, wherein they localize to major processes.

参考文献

1). OLFML2A mediates cell cycle regulation in triple-negative breast cancer via EZH2. Frontiers in oncology, 2026 (PubMed: 41607539) [IF=3.5]

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