OR11G2 Antibody - #DF5009

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製品: OR11G2 Antibody
カタログ: DF5009
タンパク質の説明: Rabbit polyclonal antibody to OR11G2
アプリケーション: WB IF/ICC
反応性: Human
分子量: 35 KD; 39kD(Calculated).
ユニプロット: Q8NGC1
RRID: AB_2837368

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
OR11G2 Antibody detects endogenous levels of total OR11G2.
RRID:
AB_2837368
引用形式: Affinity Biosciences Cat# DF5009, RRID:AB_2837368.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

O11G2_HUMAN; Olfactory receptor 11G2; Olfactory receptor family 11 subfamily G member 2; Olfactory receptor OR14-34; OR11G2; OR14-34;

免疫原

免疫原:
Uniprot:

Q8NGC1(O11G2_HUMAN) >>Visit HPA database.

遺伝子(ID):
OR11G2(390439)
タンパク質配列:
MHFLSQNDLNINLIPHLCLHRHSVIAGAFTIHRHMKIFNSPSNSSTFTGFILLGFPCPREGQILLFVLFTVVYLLTLMGNGSIICAVHWDQRLHAPMYILLANFSFLEICYVTSTVPSMLANFLSDTKIISFSGCFLQFYFFFSLGSTECFFLAVMAFDRYLAICRPLRYPTIMTRRLCTNLVVNCWVLGFIWFLIPIVNISQMSFCGSRIIDHFLCDPAPLLTLTCKKGPVIELVFSVLSPLPVFMLFLFIVGSYALVVRAVLRVPSAAGRRKAFSTCGSHLAVVSLFYGSVLVMYGSPPSKNEAGKQKTVTLFYSVVTPLLNPVIYSLRNKDMRKALKKFWGT

PTMs - Q8NGC1 基板として

Site PTM Type Enzyme
Y328 Phosphorylation
S329 Phosphorylation

研究背景

機能:

Odorant receptor.

細胞の位置付け:

Cell membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the G-protein coupled receptor 1 family.

研究領域

· Organismal Systems > Sensory system > Olfactory transduction.

参考文献

1). ALA Protects Against ERS-mediated Apoptosis in a Cochlear Cell Model With Low Citrate Synthase Expression. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS (PubMed: 32418909) [IF=3.9]

Application: WB    Species: mouse    Sample: shRNA-Cs1429 cells

Fig. 4. | Downregulation of CS expression resulted in ATF6-mediated ERS and apoptosis in HEI-OC1 cells. (A) Higher protein level of BIP, pATF6, CHOP, Cleaved Caspase12 and Bax were detected by Western blotting in shRNA-Cs1429 cells, whereas the level of Bcl-2 protein was decreased. The average grey intensity of the proteins were normalized with those of β-actin.

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