CD168 Antibody - #DF4809
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製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4809, RRID:AB_2837160.
折りたたみ／展開
CD168; CD168 antigen; HMMR; HMMR_HUMAN; Hyaluronan mediated motility receptor; Hyaluronan-mediated motility receptor (RHAMM); IHABP; Intracellular hyaluronic acid-binding protein; MGC119494; MGC119495; OTTHUMP00000196920; Receptor for hyaluronan-mediated motility; RHAMM;
免疫原
- O75330 HMMR_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSFPKAPLKRFNDPSGCAPSPGAYDVKTLEVLKGPVSFQKSQRFKQQKESKQNLNVDKDTTLPASARKVKSSESKESQKNDKDLKILEKEIRVLLQERGAQDRRIQDLETELEKMEARLNAALREKTSLSANNATLEKQLIELTRTNELLKSKFSENGNQKNLRILSLELMKLRNKRETKMRGMMAKQEGMEMKLQVTQRSLEESQGKIAQLEGKLVSIEKEKIDEKSETEKLLEYIEEISCASDQVEKYKLDIAQLEENLKEKNDEILSLKQSLEENIVILSKQVEDLNVKCQLLEKEKEDHVNRNREHNENLNAEMQNLKQKFILEQQEREKLQQKELQIDSLLQQEKELSSSLHQKLCSFQEEMVKEKNLFEEELKQTLDELDKLQQKEEQAERLVKQLEEEAKSRAEELKLLEEKLKGKEAELEKSSAAHTQATLLLQEKYDSMVQSLEDVTAQFESYKALTASEIEDLKLENSSLQEKAAKAGKNAEDVQHQILATESSNQEYVRMLLDLQTKSALKETEIKEITVSFLQKITDLQNQLKQQEEDFRKQLEDEEGRKAEKENTTAELTEEINKWRLLYEELYNKTKPFQLQLDAFEVEKQALLNEHGAAQEQLNKIRDSYAKLLGHQNLKQKIKHVVKLKDENSQLKSEVSKLRCQLAKKKQSETKLQEELNKVLGIKHFDPSKAFHHESKENFALKTPLKEGNTNCYRAPMECQESWK
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - O75330 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S2 | Phosphorylation | Uniprot | |
| S20 | Phosphorylation | Uniprot | |
| S41 | Phosphorylation | Uniprot | |
| S65 | Phosphorylation | Uniprot | |
| T110 | Phosphorylation | Uniprot | |
| K114 | Ubiquitination | Uniprot | |
| K138 | Ubiquitination | Uniprot | |
| T198 | Phosphorylation | Uniprot | |
| S205 | Phosphorylation | Uniprot | |
| K215 | Ubiquitination | Uniprot | |
| K221 | Ubiquitination | Uniprot | |
| Y250 | Phosphorylation | Uniprot | |
| K251 | Ubiquitination | Uniprot | |
| K338 | Ubiquitination | Uniprot | |
| K350 | Ubiquitination | Uniprot | |
| S353 | Phosphorylation | Uniprot | |
| K419 | Ubiquitination | Uniprot | |
| K489 | Ubiquitination | Uniprot | |
| K604 | Ubiquitination | Uniprot | |
| K635 | Ubiquitination | Uniprot | |
| S656 | Phosphorylation | Uniprot | |
| K696 | Ubiquitination | Uniprot | |
| T703 | Phosphorylation | Uniprot | |
| Y713 | Phosphorylation | Uniprot |
研究背景
Receptor for hyaluronic acid (HA) (By similarity). Involved in cell motility (By similarity). When hyaluronan binds to HMMR, the phosphorylation of a number of proteins, including PTK2/FAK1 occurs. May also be involved in cellular transformation and metastasis formation, and in regulating extracellular-regulated kinase (ERK) activity. May act as a regulator of adipogenisis (By similarity).
Cell surface. Cytoplasm.
Expressed in breast cancer cell lines and in normal breast tissue.
Subunit of the HARC complex. Interacts with ANKRD26.
研究領域
· Environmental Information Processing > Signaling molecules and interaction > ECM-receptor interaction. (View pathway)
参考文献
Application: WB Species: Human Sample: HepG2 cells
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