VTI1B Antibody - #DF4610
| 製品: | VTI1B Antibody |
| カタログ: | DF4610 |
| タンパク質の説明: | Rabbit polyclonal antibody to VTI1B |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog, Xenopus |
| 分子量: | 27 KD; 27kD(Calculated). |
| ユニプロット: | Q9UEU0 |
| RRID: | AB_2836974 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4610, RRID:AB_2836974.
折りたたみ／展開
HGNC:17793; V SNARE; v-SNARE; Vesicle associated soluble NSF attachment protein receptor; Vesicle transport through interaction with t SNAREs 1B; Vesicle transport through interaction with t SNAREs homolog 1B (yeast); Vesicle transport through interaction with t-SNAREs homolog 1B; Vesicle transport v-SNARE protein Vti1-like 1; VTI1; VTI1 like; Vti1 rp1; VTI1-LIKE; Vti1-rp1; VTI1B; VTI1B_HUMAN; VTI1L; VTI1L1; VTI2;
免疫原
- Q9UEU0 VTI1B_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MASSAASSEHFEKLHEIFRGLHEDLQGVPERLLGTAGTEEKKKLIRDFDEKQQEANETLAEMEEELRYAPLSFRNPMMSKLRNYRKDLAKLHREVRSTPLTATPGGRGDMKYGIYAVENEHMNRLQSQRAMLLQGTESLNRATQSIERSHRIATETDQIGSEIIEELGEQRDQLERTKSRLVNTSENLSKSRKILRSMSRKVTTNKLLLSIIILLELAILGGLVYYKFFRSH
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UEU0 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| A2 | Acetylation | Uniprot | |
| K13 | Ubiquitination | Uniprot | |
| K51 | Ubiquitination | Uniprot | |
| S72 | Phosphorylation | Uniprot | |
| K90 | Ubiquitination | Uniprot | |
| T103 | Phosphorylation | Uniprot | |
| R107 | Methylation | Uniprot | |
| Y112 | Phosphorylation | Uniprot | |
| Y115 | Phosphorylation | Uniprot | |
| S127 | Phosphorylation | Uniprot | |
| S138 | Phosphorylation | Uniprot | |
| T154 | Phosphorylation | Uniprot | |
| T156 | Phosphorylation | Uniprot | |
| S161 | Phosphorylation | Uniprot | |
| S179 | Phosphorylation | Uniprot | |
| S185 | Phosphorylation | Uniprot | |
| S189 | Phosphorylation | Uniprot | |
| K190 | Ubiquitination | Uniprot | |
| T203 | Phosphorylation | Uniprot | |
| S210 | Phosphorylation | Uniprot | |
| Y225 | Phosphorylation | Uniprot |
研究背景
V-SNARE that mediates vesicle transport pathways through interactions with t-SNAREs on the target membrane. These interactions are proposed to mediate aspects of the specificity of vesicle trafficking and to promote fusion of the lipid bilayers. May be concerned with increased secretion of cytokines associated with cellular senescence.
Early endosome membrane>Single-pass type IV membrane protein. Late endosome membrane>Single-pass type IV membrane protein. Lysosome membrane. Cytoplasmic granule. Recycling endosome membrane>Single-pass type IV membrane protein.
Expressed in all tissues examined.
Forms a SNARE complex with STX7, STX8 and VAMP8 which functions in the homotypic fusion of late endosomes. Component of the SNARE complex composed of STX7, STX8, VAMP7 and VIT1B that is required for heterotypic fusion of late endosomes with lysosomes (By similarity). May interact with STX17. Interacts with CLINT1.
Belongs to the VTI1 family.
研究領域
· Genetic Information Processing > Folding, sorting and degradation > SNARE interactions in vesicular transport.
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