製品: UBAC1 Antibody
カタログ: DF4598
タンパク質の説明: Rabbit polyclonal antibody to UBAC1
アプリケーション: WB IF/ICC
反応性: Human
予測: Zebrafish, Horse, Dog, Chicken, Xenopus
分子量: 45 KD(Observed); 45kD(Calculated).
ユニプロット: Q9BSL1
RRID: AB_2836962

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Zebrafish(80%), Horse(80%), Dog(80%), Chicken(80%), Xenopus(90%)
クローナリティ:
Polyclonal
特異性:
UBAC1 Antibody detects endogenous levels of total UBAC1.
RRID:
AB_2836962
引用形式: Affinity Biosciences Cat# DF4598, RRID:AB_2836962.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

1110033G07Rik; AA407978; E3 ubiquitin-protein ligase subunit KPC2; GBDR1; Glialblastoma cell differentiation-related protein 1; Glialblastoma differentiation-related protein 1; Kip1 ubiquitination-promoting complex protein 2; kpc 2; Kpc2; OTTHUMP00000022563; Putative glialblastoma cell differentiation-related protein; RP11-432J22.3; UBA domain containing 1; UBA domain-containing protein 1; UBAC 1; UBAC1; Ubadc1; Ubiquitin associated domain containing 1; Ubiquitin-associated domain-containing protein 1;

免疫原

免疫原:

A synthesized peptide derived from human UBAC1, corresponding to a region within the internal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
Q9BSL1 UBAC1_HUMAN:

Ubiquitous.

タンパク質配列:
MFVQEEKIFAGKVLRLHICASDGAEWLEEATEDTSVEKLKERCLKHCAHGSLEDPKSITHHKLIHAASERVLSDARTILEENIQDQDVLLLIKKRAPSPLPKMADVSAEEKKKQDQKAPDKEAILRATANLPSYNMDRAAVQTNMRDFQTELRKILVSLIEVAQKLLALNPDAVELFKKANAMLDEDEDERVDEAALRQLTEMGFPENRATKALQLNHMSVPQAMEWLIEHAEDPTIDTPLPGQAPPEAEGATAAASEAAAGASATDEEARDELTEIFKKIRRKREFRADARAVISLMEMGFDEKEVIDALRVNNNQQNAACEWLLGDRKPSPEELDKGIDPDSPLFQAILDNPVVQLGLTNPKTLLAFEDMLENPLNSTQWMNDPETGPVMLQISRIFQTLNRT

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Xenopus
90
Horse
80
Dog
80
Zebrafish
80
Chicken
80
Pig
70
Bovine
70
Sheep
60
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Ubiquitous.

Restrictive clause

 

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