TAF3 Antibody - #DF4575
| 製品: | TAF3 Antibody |
| カタログ: | DF4575 |
| タンパク質の説明: | Rabbit polyclonal antibody to TAF3 |
| アプリケーション: | WB IHC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Zebrafish, Bovine, Rabbit, Dog, Chicken, Xenopus |
| 分子量: | 100 KD; 104kD(Calculated). |
| ユニプロット: | Q5VWG9 |
| RRID: | AB_2836939 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4575, RRID:AB_2836939.
折りたたみ／展開
140 kDa TATA box-binding protein-associated factor; Bip2 protein; RNA polymerase II transcription factor TAFII140; TAF(II)140; TAF140; TAF3; TAF3 RNA polymerase II TATA box binding protein (TBP)-associated factor; TAF3_HUMAN; TAFII-140; TAFII140; TAFII155 protein; TATA box binding protein associated factor 3; TBP-associated factor 3; Transcription initiation factor TFIID 140 kDa subunit; Transcription initiation factor TFIID subunit 3;
免疫原
- Q5VWG9 TAF3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MCESYSRSLLRVSVAQICQALGWDSVQLSACHLLTDVLQRYLQQLGRGCHRYSELYGRTDPILDDVGEAFQLMGVSLHELEDYIHNIEPVTFPHQIPSFPVSKNNVLQFPQPGSKDAEERKEYIPDYLPPIVSSQEEEEEEQVPTDGGTSAEAMQVPLEEDDELEEEEIINDENFLGKRPLDSPEAEELPAMKRPRLLSTKGDTLDVVLLEAREPLSSINTQKIPPMLSPVHVQDSTDLAPPSPEPPMLAPVAKSQMPTAKPLETKSFTPKTKTKTSSPGQKTKSPKTAQSPAMVGSPIRSPKTVSKEKKSPGRSKSPKSPKSPKVTTHIPQTPVRPETPNRTPSATLSEKISKETIQVKQIQTPPDAGKLNSENQPKKAVVADKTIEASIDAVIARACAEREPDPFEFSSGSESEGDIFTSPKRISGPECTTPKASTSANNFTKSGSTPLPLSGGTSSSDNSWTMDASIDEVVRKAKLGTPSNMPPNFPYISSPSVSPPTPEPLHKVYEEKTKLPSSVEVKKKLKKELKTKMKKKEKQRDREREKDKNKDKSKEKDKVKEKEKDKETGRETKYPWKEFLKEEEADPYKFKIKEFEDVDPKVKLKDGLVRKEKEKHKDKKKDREKGKKDKDKREKEKVKDKGREDKMKAPAPPLVLPPKELALPLFSPATASRVPAMLPSLLPVLPEKLFEEKEKVKEKEKKKDKKEKKKKKEKEKEKKEKEREKEKREREKREKEKEKHKHEKIKVEPVALAPSPVIPRLTLRVGAGQDKIVISKVVPAPEAKPAPSQNRPKTPPPAPAPAPGPMLVSPAPVPLPLLAQAAAGPALLPSPGPAASGASAKAPVRSVVTETVSTYVIRDEWGNQIWICPGCNKPDDGSPMIGCDDCDDWYHWPCVGIMTAPPEEMQWFCPKCANKKKDKKHKKRKHRAH
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q5VWG9 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y52 | Phosphorylation | Uniprot | |
| Y56 | Phosphorylation | Uniprot | |
| S114 | Phosphorylation | Uniprot | |
| S183 | Phosphorylation | Uniprot | |
| S199 | Phosphorylation | Uniprot | |
| T200 | Phosphorylation | Uniprot | |
| T204 | Phosphorylation | Uniprot | |
| S229 | Phosphorylation | Uniprot | |
| S236 | Phosphorylation | Uniprot | |
| T237 | Phosphorylation | Uniprot | |
| S243 | Phosphorylation | Uniprot | |
| K261 | Acetylation | Uniprot | |
| T265 | Phosphorylation | Uniprot | |
| K266 | Acetylation | Uniprot | |
| S267 | Phosphorylation | Uniprot | |
| T269 | Phosphorylation | Uniprot | |
| T288 | Phosphorylation | Uniprot | |
| S291 | Phosphorylation | Uniprot | |
| S297 | Phosphorylation | Uniprot | |
| S301 | Phosphorylation | Uniprot | |
| S315 | Phosphorylation | Uniprot | |
| S317 | Phosphorylation | Uniprot | |
| S320 | Phosphorylation | Uniprot | |
| S323 | Phosphorylation | Uniprot | |
| T333 | Phosphorylation | Uniprot | |
| T339 | Phosphorylation | Uniprot | |
| T343 | Phosphorylation | Uniprot | |
| T347 | Phosphorylation | Uniprot | |
| S349 | Phosphorylation | Uniprot | |
| T364 | Phosphorylation | Uniprot | |
| K370 | Ubiquitination | Uniprot | |
| S373 | Phosphorylation | Uniprot | |
| S410 | Phosphorylation | Uniprot | |
| S411 | Phosphorylation | Uniprot | |
| S413 | Phosphorylation | Uniprot | |
| S415 | Phosphorylation | Uniprot | |
| S427 | Phosphorylation | Uniprot | |
| T432 | Phosphorylation | Uniprot | |
| T433 | Phosphorylation | Uniprot | |
| S483 | Phosphorylation | Uniprot | |
| Y491 | Phosphorylation | Uniprot | |
| S493 | Phosphorylation | Uniprot | |
| S494 | Phosphorylation | Uniprot | |
| S496 | Phosphorylation | Uniprot | |
| S498 | Phosphorylation | Uniprot | |
| T501 | Phosphorylation | Uniprot | |
| S517 | Phosphorylation | Uniprot | |
| S518 | Phosphorylation | Uniprot | |
| T568 | Phosphorylation | Uniprot | |
| T572 | Phosphorylation | Uniprot | |
| K601 | Acetylation | Uniprot | |
| K621 | Acetylation | Uniprot | |
| K625 | Acetylation | Uniprot | |
| K628 | Acetylation | Uniprot | |
| S667 | Phosphorylation | Uniprot | |
| K746 | Sumoylation | Uniprot | |
| S755 | Phosphorylation | Uniprot | |
| T762 | Phosphorylation | Uniprot | |
| K776 | Acetylation | Uniprot | |
| T794 | Phosphorylation | Uniprot | |
| S809 | Phosphorylation | Uniprot |
研究背景
Transcription factor TFIID is one of the general factors required for accurate and regulated initiation by RNA polymerase II. TFIID is a multimeric protein complex that plays a central role in mediating promoter responses to various activators and repressors. Required in complex with TBPL2 for the differentiation of myoblasts into myocytes. The complex replaces TFIID at specific promoters at an early stage in the differentiation process.
Nucleus.
Belongs to the TFIID complex which is composed of TATA binding protein (TBP) and a number of TBP-associated factors (TAFs). Interacts with TAF10 via the histone fold. Interacts with TAF13, TBP, SAP130 and GCN5L2. Interacts with TBPL2.
The PHD-type zinc finger mediates binding to histone H3 methyllysine at position 4 (H3K4me3).
Belongs to the TAF3 family.
研究領域
· Genetic Information Processing > Transcription > Basal transcription factors.
· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.
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