STMN3 Antibody - #DF4546

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製品: STMN3 Antibody
カタログ: DF4546
タンパク質の説明: Rabbit polyclonal antibody to STMN3
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Dog, Chicken
分子量: 21 KD(Observed); 21kD(Calculated).
ユニプロット: Q9NZ72
RRID: AB_2836897

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STMN3 Peptide

1mg
関連ダウンロード
Antigen/Blocking Peptide MS Report
Antigen/Blocking Peptide HPLC Report
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(88%), Bovine(100%), Horse(88%), Sheep(88%), Dog(88%), Chicken(88%)
クローナリティ:
Polyclonal
特異性:
STMN3 Antibody detects endogenous levels of total STMN3.
RRID:
AB_2836897
引用形式: Affinity Biosciences Cat# DF4546, RRID:AB_2836897.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

AI604839; R75323; RP23-83A14.1; SCG10-like protein; Scgn10 like protein; Sclip; Stathmin like 3; Stathmin-3; STMN3; STMN3_HUMAN;

免疫原

免疫原:

A synthesized peptide derived from human STMN3, corresponding to a region within the internal amino acids.

Uniprot:

Q9NZ72(STMN3_HUMAN) >>Visit HPA database.

遺伝子(ID):
STMN3(50861)
発現特異性:
Q9NZ72 STMN3_HUMAN:

Neuron specific.

タンパク質配列:
MASTISAYKEKMKELSVLSLICSCFYTQPHPNTVYQYGDMEVKQLDKRASGQSFEVILKSPSDLSPESPMLSSPPKKKDTSLEELQKRLEAAEERRKTQEAQVLKQLAERREHEREVLHKALEENNNFSRQAEEKLNYKMELSKEIREAHLAALRERLREKELHAAEVRRNKEQREEMSG

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
100
Pig
88
Horse
88
Sheep
88
Dog
88
Chicken
88
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Exhibits microtubule-destabilizing activity, which is antagonized by STAT3.

PTMs:

N-terminal palmitoylation promotes specific anchoring to the cytosolic leaflet of Golgi membranes and subsequent vesicular trafficking along dendrites and axons. Neuronal Stathmins are substrates for palmitoyltransferases ZDHHC3, ZDHHC7 and ZDHHC15.

細胞の位置付け:

Golgi apparatus. Cell projection>Growth cone. Cell projection>Axon. Cytoplasm>Cytosol.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Neuron specific.

タンパク質ファミリー:

Belongs to the stathmin family.

Restrictive clause

 

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