製品: RASL10A Antibody
カタログ: DF4390
タンパク質の説明: Rabbit polyclonal antibody to RASL10A
アプリケーション: WB IF/ICC
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Dog
分子量: 30 KD(Observed); 23kD(Calculated).
ユニプロット: Q92737
RRID: AB_2836745

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(100%), Bovine(100%), Horse(100%), Sheep(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
RASL10A Antibody detects endogenous levels of total RASL10A.
RRID:
AB_2836745
引用形式: Affinity Biosciences Cat# DF4390, RRID:AB_2836745.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Ras like protein family member 10A; Ras like protein RRP22; RAS like, family 10, member A; RAS related on chromosome 22; Ras related protein on chromosome 22; Ras related protein on chromosome 22 homolog; Ras-like protein family member 10A; Ras-like protein RRP22; Ras-related protein on chromosome 22; RASL 10A; Rasl10a; RASL10A protein; Rasl10a RAS like, family 10, member A; RRP 22; RRP22; RSLAA_HUMAN;

免疫原

免疫原:

A synthesized peptide derived from human RASL10A, corresponding to a region within the internal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
Q92737 RSLAA_HUMAN:

Expression appears to be strictly limited to the central nervous system.

タンパク質配列:
MGGSLRVAVLGAPGVGKTAIIRQFLFGDYPERHRPTDGPRLYRPAVLLDGAVYDLSIRDGDVAGPGSSPGGPEEWPDAKDWSLQDTDAFVLVYDICSPDSFDYVKALRQRIAETRPAGAPEAPILVVGNKRDRQRLRFGPRRALAALVRRGWRCGYLECSAKYNWHVLRLFRELLRCALVRARPAHPALRLQGALHPARCSLM

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Dog
100
Zebrafish
75
Xenopus
71
Chicken
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Potent inhibitor of cellular proliferation.

PTMs:

Isoprenylation is essential for nucleolar localization, and the proliferation-inhibiting activity of RASL10A.

細胞の位置付け:

Cell membrane>Lipid-anchor>Cytoplasmic side. Nucleus>Nucleolus.
Note: May cycle in and out of the nucleolus in a GTP-dependent manner.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expression appears to be strictly limited to the central nervous system.

タンパク質ファミリー:

Belongs to the small GTPase superfamily. Ras family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.