製品: FNTB Antibody
カタログ: DF4339
タンパク質の説明: Rabbit polyclonal antibody to FNTB
アプリケーション: WB IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Zebrafish, Bovine, Rabbit, Dog
分子量: 49 KD; 49kD(Calculated).
ユニプロット: P49356
RRID: AB_2836707

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Zebrafish(89%), Bovine(100%), Rabbit(100%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
FNTB Antibody detects endogenous levels of total FNTB.
RRID:
AB_2836707
引用形式: Affinity Biosciences Cat# DF4339, RRID:AB_2836707.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

CAAX farnesyltransferase subunit beta; EC 2.5.1.58; EC=2.5.1.58; Farnesyltransferase; farnesyltransferase CAAX box beta1; farnesyltransferase, CAAX box, beta; FNTB; FNTB_HUMAN; FPTB; FTase beta; FTase-beta; MGC105303; Protein farnesyltransferase subunit beta; RAS proteins prenyltransferase beta; Ras proteins prenyltransferase subunit beta;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MASPSSFTYYCPPSSSPVWSEPLYSLRPEHARERLQDDSVETVTSIEQAKVEEKIQEVFSSYKFNHLVPRLVLQREKHFHYLKRGLRQLTDAYECLDASRPWLCYWILHSLELLDEPIPQIVATDVCQFLELCQSPEGGFGGGPGQYPHLAPTYAAVNALCIIGTEEAYDIINREKLLQYLYSLKQPDGSFLMHVGGEVDVRSAYCAASVASLTNIITPDLFEGTAEWIARCQNWEGGIGGVPGMEAHGGYTFCGLAALVILKRERSLNLKSLLQWVTSRQMRFEGGFQGRCNKLVDGCYSFWQAGLLPLLHRALHAQGDPALSMSHWMFHQQALQEYILMCCQCPAGGLLDKPGKSRDFYHTCYCLSGLSIAQHFGSGAMLHDVVLGVPENALQPTHPVYNIGPDKVIQATTYFLQKPVPGFEELKDETSAEPATD

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Dog
100
Rabbit
100
Zebrafish
89
Xenopus
78
Horse
0
Sheep
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P49356 基板として

Site PTM Type Enzyme
S3 Phosphorylation
S16 Phosphorylation
S39 Phosphorylation
T42 Phosphorylation
K50 Ubiquitination
K54 Ubiquitination
K63 Ubiquitination
K176 Ubiquitination
Y300 Phosphorylation
K418 Ubiquitination
T436 Phosphorylation

研究背景

機能:

Essential subunit of the farnesyltransferase complex. Catalyzes the transfer of a farnesyl moiety from farnesyl diphosphate to a cysteine at the fourth position from the C-terminus of several proteins having the C-terminal sequence Cys-aliphatic-aliphatic-X.

サブユニット構造:

Heterodimer of FNTA and FNTB.

タンパク質ファミリー:

Belongs to the protein prenyltransferase subunit beta family.

研究領域

· Metabolism > Metabolism of terpenoids and polyketides > Terpenoid backbone biosynthesis.

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