PABPC5 Antibody - #DF4303
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4303, RRID:AB_2836654.
折りたたみ／展開
PABP5; Poly(A) binding protein 5; Poly(A) binding protein cytoplasmic 5; Polyadenylate binding protein 5;
免疫原
- Q96DU9 PABP5_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGSGEPNPAGKKKKYLKAALYVGDLDPDVTEDMLYKKFRPAGPLRFTRICRDPVTRSPLGYGYVNFRFPADAEWALNTMNFDLINGKPFRLMWSQPDDRLRKSGVGNIFIKNLDKSIDNRALFYLFSAFGNILSCKVVCDDNGSKGYAYVHFDSLAAANRAIWHMNGVRLNNRQVYVGRFKFPEERAAEVRTRDRATFTNVFVKNIGDDIDDEKLKELFCEYGPTESVKVIRDASGKSKGFGFVRYETHEAAQKAVLDLHGKSIDGKVLYVGRAQKKIERLAELRRRFERLRLKEKSRPPGVPIYIKNLDETINDEKLKEEFSSFGSISRAKVMMEVGQGKGFGVVCFSSFEEATKAVDEMNGRIVGSKPLHVTLGQARRRC
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q96DU9 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y15 | Phosphorylation | Uniprot | |
| Y35 | Phosphorylation | Uniprot | |
| K102 | Ubiquitination | Uniprot | |
| S103 | Phosphorylation | Uniprot | |
| K111 | Acetylation | Uniprot | |
| K111 | Ubiquitination | Uniprot | |
| K115 | Ubiquitination | Uniprot | |
| Y147 | Phosphorylation | Uniprot | |
| Y149 | Phosphorylation | Uniprot | |
| S154 | Phosphorylation | Uniprot | |
| T199 | Phosphorylation | Uniprot | |
| S235 | Phosphorylation | Uniprot | |
| S238 | Phosphorylation | Uniprot | |
| Y270 | Phosphorylation | Uniprot |
研究背景
Binds the poly(A) tail of mRNA. May be involved in cytoplasmic regulatory processes of mRNA metabolism. Can probably bind to cytoplasmic RNA sequences other than poly(A) in vivo (By similarity).
Cytoplasm.
Mitochondrion matrix.
Note: Co-fractionates with mtDNA and co-immunoprecipitates with the mitochondrial poly(A) polymerase.
Expressed in fetal brain and in a range of adult tissues.
研究領域
· Genetic Information Processing > Translation > RNA transport.
· Genetic Information Processing > Translation > mRNA surveillance pathway.
· Genetic Information Processing > Folding, sorting and degradation > RNA degradation.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.