製品: PEX3 Antibody
カタログ: DF4282
タンパク質の説明: Rabbit polyclonal antibody to PEX3
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog, Chicken, Xenopus
分子量: 42 KD; 42kD(Calculated).
ユニプロット: P56589
RRID: AB_2836633

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Bovine(100%), Horse(90%), Sheep(100%), Rabbit(90%), Dog(100%), Chicken(100%), Xenopus(80%)
クローナリティ:
Polyclonal
特異性:
PEX3 Antibody detects endogenous levels of total PEX3.
RRID:
AB_2836633
引用形式: Affinity Biosciences Cat# DF4282, RRID:AB_2836633.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Peroxin-3; Peroxisomal assembly protein PEX3; Peroxisomal biogenesis factor 3; PEX3; PEX3_HUMAN; TRG18;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P56589 PEX3_HUMAN:

Found in all examined tissues.

タンパク質配列:
MLRSVWNFLKRHKKKCIFLGTVLGGVYILGKYGQKKIREIQEREAAEYIAQARRQYHFESNQRTCNMTVLSMLPTLREALMQQLNSESLTALLKNRPSNKLEIWEDLKIISFTRSTVAVYSTCMLVVLLRVQLNIIGGYIYLDNAAVGKNGTTILAPPDVQQQYLSSIQHLLGDGLTELITVIKQAVQKVLGSVSLKHSLSLLDLEQKLKEIRNLVEQHKSSSWINKDGSKPLLCHYMMPDEETPLAVQACGLSPRDITTIKLLNETRDMLESPDFSTVLNTCLNRGFSRLLDNMAEFFRPTEQDLQHGNSMNSLSSVSLPLAKIIPIVNGQIHSVCSETPSHFVQDLLTMEQVKDFAANVYEAFSTPQQLEK

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Dog
100
Chicken
100
Horse
90
Rabbit
90
Xenopus
80
Zebrafish
60
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P56589 基板として

Site PTM Type Enzyme
Y27 Phosphorylation
Y48 Phosphorylation
T75 Phosphorylation
K100 Ubiquitination
K189 Ubiquitination
K197 Ubiquitination
S201 Phosphorylation
K208 Ubiquitination
K220 Ubiquitination
S221 Phosphorylation
K227 Ubiquitination
S254 Phosphorylation
T260 Phosphorylation
K262 Ubiquitination
S311 Phosphorylation

研究背景

機能:

Involved in peroxisome biosynthesis and integrity. Assembles membrane vesicles before the matrix proteins are translocated. As a docking factor for PEX19, is necessary for the import of peroxisomal membrane proteins in the peroxisomes.

細胞の位置付け:

Peroxisome membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Found in all examined tissues.

サブユニット構造:

Interacts with PEX19.

タンパク質ファミリー:

Belongs to the peroxin-3 family.

研究領域

· Cellular Processes > Transport and catabolism > Peroxisome.   (View pathway)

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