NXF3 Antibody - #DF4258
| 製品: | NXF3 Antibody |
| カタログ: | DF4258 |
| タンパク質の説明: | Rabbit polyclonal antibody to NXF3 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human |
| 予測: | Dog |
| 分子量: | 60 KD; 60kD(Calculated). |
| ユニプロット: | Q9H4D5 |
| RRID: | AB_2836609 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4258, RRID:AB_2836609.
折りたたみ／展開
Nuclear RNA export factor 3; NXF3; NXF3_HUMAN; OTTHUMP00000023726; OTTHUMP00000023727; TAP like protein 3; TAP-like protein 3; TAPL 3; TAPL-3; TAPL3;
免疫原
- Q9H4D5 NXF3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MSLPSGHTTGHTDQVVQRRARCWDIYQRRFSSRSEPVNPGMHSSSHQQQDGDAAMHGAHMDSPVRYTPYTISPYNRKGSFRKQDQTHVNMEREQKPPERRMEGNMPDGTLGSWFKITVPFGIKYNEKWLLNLIQNECSVPFVPVEFHYENMHASFFVENASIAYALKNVSGKIWDEDNEKISIFVNPAGIPHFVHRELKSEKVEQIKLAMNQQCDVSQEALDIQRLPFYPDMVNRDTKMASNPRKCMAASLDVHEENIPTVMSAGEMDKWKGIEPGEKCADRSPVCTTFSDTSSNINSILELFPKLLCLDGQQSPRATLCGTEAHKRLPTCKGSFFGSEMLKNLVLQFLQQYYLIYDSGDRQGLLSAYHDEACFSLSIPFNPEDSAPSSFCKFFKDSRNIKILKDPYLRGELLKHTKLDIVDSLSALPKTQHDLSSFLVDMWYQTEWMLCFSVNGVFKEVEGQSQGSVLAFTRTFIATPGSSSSLCIVNDKLFVRDTSHQGTQSALFTLVPTAFSSSVPAFSQEQQKMLPS
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9H4D5 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| Y124 | Phosphorylation | Uniprot | |
| Y407 | Phosphorylation | Uniprot |
研究背景
May function as a tissue-specific nuclear mRNA export factor.
Nucleus. Cytoplasm.
Note: Shuttles between the nucleus and the cytoplasm.
Expressed at high level in testis and at low level in a small number of tissues.
Interacts with NXT1, NXT2, E1B-AP5 and CRM1 nuclear export factor.
Lacks C-terminal domain that mediates direct interactions with nucleoporins.
Contains a novel CRM1-dependent nuclear export signal that compensates in cis for the loss of the nuclear pore targeting domain.
The RNA-binding domain is a non-canonical RNP-type domain.
Belongs to the NXF family.
研究領域
· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.
· Genetic Information Processing > Translation > RNA transport.
· Genetic Information Processing > Translation > mRNA surveillance pathway.
· Human Diseases > Infectious diseases: Viral > Influenza A.
· Human Diseases > Infectious diseases: Viral > Herpes simplex infection.
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