製品: NARFL Antibody
カタログ: DF4253
タンパク質の説明: Rabbit polyclonal antibody to NARFL
アプリケーション: WB IF/ICC
反応性: Human
予測: Bovine, Chicken
分子量: 50 KD; 53kD(Calculated).
ユニプロット: Q9H6Q4
RRID: AB_2836604

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Bovine(88%), Chicken(88%)
クローナリティ:
Polyclonal
特異性:
NARFL Antibody detects endogenous levels of total NARFL.
RRID:
AB_2836604
引用形式: Affinity Biosciences Cat# DF4253, RRID:AB_2836604.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Cytosolic Fe-S cluster assembly factor NARFL; FLJ21988; HPRN; IOP1; Iron only hydrogenase like protein 1; iron-only hydrogenase-like protein 1; LET1 like/JFP15; LET1L; Nuclear prelamin A recognition factor like; Nuclear prelamin A recognition factor like protein; nuclear prelamin A recognition factor-like protein; PRN; Protein related to Narf; uclear prelamin A recognition factor-like;

免疫原

免疫原:

A synthesized peptide derived from human NARFL, corresponding to a region within the internal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
Q9H6Q4 CIAO3_HUMAN:

Widely expressed.

タンパク質配列:
MASPFSGALQLTDLDDFIGPSQECIKPVKVEKRAGSGVAKIRIEDDGSYFQINQDGGTRRLEKAKVSLNDCLACSGCITSAETVLITQQSHEELKKVLDANKMAAPSQQRLVVVSVSPQSRASLAARFQLNPTDTARKLTSFFKKIGVHFVFDTAFSRHFSLLESQREFVRRFRGQADCRQALPLLASACPGWICYAEKTHGSFILPHISTARSPQQVMGSLVKDFFAQQQHLTPDKIYHVTVMPCYDKKLEASRPDFFNQEHQTRDVDCVLTTGEVFRLLEEEGVSLPDLEPAPLDSLCSGASAEEPTSHRGGGSGGYLEHVFRHAARELFGIHVAEVTYKPLRNKDFQEVTLEKEGQVLLHFAMAYGFRNIQNLVQRLKRGRCPYHYVEVMACPSGCLNGGGQLQAPDRPSRELLQHVERLYGMVRAEAPEDAPGVQELYTHWLQGTDSECAGRLLHTQYHAVEKASTGLGIRW

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Bovine
88
Chicken
88
Zebrafish
50
Pig
0
Horse
0
Sheep
0
Dog
0
Xenopus
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into extramitochondrial Fe/S proteins. Seems to negatively regulate the level of HIF1A expression, although this effect could be indirect.

組織特異性:

Widely expressed.

タンパク質ファミリー:

Belongs to the NARF family.

Restrictive clause

 

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