製品: LIPI Antibody
カタログ: DF4141
タンパク質の説明: Rabbit polyclonal antibody to LIPI
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
分子量: 53 KD(Observed); 53kD(Calculated).
ユニプロット: Q6XZB0
RRID: AB_2836506

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
クローナリティ:
Polyclonal
特異性:
LIPI Antibody detects endogenous levels of total LIPI.
RRID:
AB_2836506
引用形式: Affinity Biosciences Cat# DF4141, RRID:AB_2836506.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Cancer/testis antigen 17; CT17; Lipase member I; LIPI; LIPI_HUMAN; LPD lipase; LPDL; Membrane-associated phosphatidic acid-selective phospholipase A1-beta; membrane-associated phospholipase A1 beta 7B+; membrane-associated phospholipase A1 beta deltaE2-3; membrane-associated phospholipase A1 beta deltaE5; membrane-associated phospholipase A1 beta deltaE6.1; membrane-associated phospholipase A1 beta deltaE7.2; membrane-associated phospholipase A1 beta deltaE8-9; membrane-associated phospholipase A1 beta fl; mPA-PLA1 beta; PLA1C; PRED5;

免疫原

免疫原:

A synthesized peptide derived from human LIPI, corresponding to a region within the internal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
Q6XZB0 LIPI_HUMAN:

Expressed in testis. Expressed exclusively at the connecting piece of the sperm.

タンパク質配列:
MRVYIFLCLMCWVRSDNKRPCLEFSQLSVKDSFRDLFIPRIETILMMYTRNNLNCAEPLFEQNNSLNVNFNTQKKTVWLIHGYRPVGSIPLWLQNFVRILLNEEDMNVIVVDWSRGATTFIYNRAVKNTRKVAVSLSVHIKNLLKHGASLDNFHFIGVSLGAHISGFVGKIFHGQLGRITGLDPAGPRFSRKPPYSRLDYTDAKFVDVIHSDSNGLGIQEPLGHIDFYPNGGNKQPGCPKSIFSGIQFIKCNHQRAVHLFMASLETNCNFISFPCRSYKDYKTSLCVDCDCFKEKSCPRLGYQAKLFKGVLKERMEGRPLRTTVFLDTSGTYPFCTYYFVLSIIVPDKTMMDGSFSFKLLNQLGMIEEPRLYEKNKPFYKLQEVKILAQFYNDFVNISSIGLTYFQSSNLQCSTCTYKIQSLMLKSLTYPERPPLCRYNIVLKDREEVFLNPNTCTPKNT

研究背景

機能:

Hydrolyzes specifically phosphatidic acid (PA) to produce 2-acyl lysophosphatidic acid (LPA; a potent bioactive lipid mediator) and fatty acid. Does not hydrolyze other phospholipids, like phosphatidylserine (PS), phosphatidylcholine (PC) and phosphatidylethanolamine (PE) or triacylglycerol (TG).

細胞の位置付け:

Membrane. Secreted.
Note: May associate with lipid draft.

Membrane. Secreted.
Note: May associate with lipid draft.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Expressed in testis. Expressed exclusively at the connecting piece of the sperm.

タンパク質ファミリー:

Belongs to the AB hydrolase superfamily. Lipase family.

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

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