製品: GHITM Antibody
カタログ: DF4093
タンパク質の説明: Rabbit polyclonal antibody to GHITM
アプリケーション: WB IHC IF/ICC
反応性: Human
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 37 KD; 37kD(Calculated).
ユニプロット: Q9H3K2
RRID: AB_2836467

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Pig(100%), Bovine(100%), Horse(91%), Sheep(100%), Rabbit(100%), Dog(82%)
クローナリティ:
Polyclonal
特異性:
GHITM Antibody detects endogenous levels of total GHITM.
RRID:
AB_2836467
引用形式: Affinity Biosciences Cat# DF4093, RRID:AB_2836467.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Dermal papilla derived protein 2; Dermal papilla-derived protein 2; DERP2; Ghitm; GHITM_HUMAN; Growth hormone inducible transmembrane protein; Growth hormone-inducible transmembrane protein; HSPC282; MICS1; Mitochondrial morphology and cristae structure 1; My021; PTD010; TMBIM5; Transmembrane BAX inhibitor motif containing 5; Transmembrane BAX inhibitor motif containing protein 5; Transmembrane BAX inhibitor motif-containing protein 5;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MLAARLVCLRTLPSRVFHPAFTKASPVVKNSITKNQWLLTPSREYATKTRIGIRRGRTGQELKEAALEPSMEKIFKIDQMGRWFVAGGAAVGLGALCYYGLGLSNEIGAIEKAVIWPQYVKDRIHSTYMYLAGSIGLTALSAIAISRTPVLMNFMMRGSWVTIGVTFAAMVGAGMLVRSIPYDQSPGPKHLAWLLHSGVMGAVVAPLTILGGPLLIRAAWYTAGIVGGLSTVAMCAPSEKFLNMGAPLGVGLGLVFVSSLGSMFLPPTTVAGATLYSVAMYGGLVLFSMFLLYDTQKVIKRAEVSPMYGVQKYDPINSMLSIYMDTLNIFMRVATMLATGGNRKK

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Bovine
100
Sheep
100
Rabbit
100
Horse
91
Dog
82
Xenopus
75
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9H3K2 基板として

Site PTM Type Enzyme
K23 Ubiquitination
K29 Ubiquitination
K34 Ubiquitination
T40 Phosphorylation
K63 Ubiquitination
S70 Phosphorylation
K73 Ubiquitination
S185 Phosphorylation
Y313 Phosphorylation

研究背景

機能:

Required for the mitochondrial tubular network and cristae organization. Involved in apoptotic release of cytochrome c.

細胞の位置付け:

Mitochondrion inner membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the BI1 family.

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