Myoglobin Antibody - #BF0424
(1)
製品説明
ソース:
Mouse
アプリケーション:
ELISA 1:10000, WB 1:500-1:2000, IHC 1:200-1:1000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human
クローナリティ:
Monoclonal [AFB1557]
特異性:
Myoglobin antibody detects endogenous levels of total Myoglobin.
RRID:
AB_2833582
引用形式: Affinity Biosciences Cat# BF0424, RRID:AB_2833582.
引用形式: Affinity Biosciences Cat# BF0424, RRID:AB_2833582.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Mouse IgG1 in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
MB; MGC13548; MYG_HUMAN; Myoglobin; PVALB;
免疫原
免疫原:
Purified recombinant fragment of human Myoglobin expressed in E. Coli.
Uniprot:
遺伝子(ID):
タンパク質の説明:
Myoglobin (MB), with 154-amino acid protein (about 17kDa), is a member of the globin superfamily and expression of myoglobin is highest in skeletal and cardiac muscle. Functionally, myoglobin is well accepted as an O2-storage protein in muscle, capable of releasing O2 during periods of hypoxia or anoxia. Myoglobin is also thought to buffer intracellular O2 concentration when muscle activity increases and to facilitate intracellular O2 diffusion by providing a parallel path that augments simple diffusion of dissolved O2. Furthermore, myoglobin is used together with cTnI or cTnT in clinical practise for better specificity in AMI diagnosis.
タンパク質配列:
- P02144 MYG_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGLSDGEWQLVLNVWGKVEADIPGHGQEVLIRLFKGHPETLEKFDKFKHLKSEDEMKASEDLKKHGATVLTALGGILKKKGHHEAEIKPLAQSHATKHKIPVKYLEFISECIIQVLQSKHPGDFGADAQGAMNKALELFRKDMASNYKELGFQG
研究背景
機能:
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
タンパク質ファミリー:
Belongs to the globin family.
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