GNAT2 Antibody - #DF4110
| 製品: | GNAT2 Antibody |
| カタログ: | DF4110 |
| タンパク質の説明: | Rabbit polyclonal antibody to GNAT2 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 予測: | Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog, Chicken |
| 分子量: | 40 KD; 40kD(Calculated). |
| ユニプロット: | P19087 |
| RRID: | AB_2836401 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4110, RRID:AB_2836401.
折りたたみ／展開
ACHM4; Cone type transducin alpha subunit; GNAT 2; GNAT C; Gnat2; GNAT2_HUMAN; GNATC; Guanine nucleotide binding protein (G protein) alpha transducing activity polypeptide 2; Guanine nucleotide binding protein G t subunit alpha 2; Guanine nucleotide-binding protein G(t) subunit alpha-2; Transducin alpha 2; Transducin alpha-2 chain; Transducin alpha2; Transducin cone specific alpha polypeptide;
免疫原
- P19087 GNAT2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MGSGASAEDKELAKRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDGYSPEECLEFKAIIYGNVLQSILAIIRAMTTLGIDYAEPSCADDGRQLNNLADSIEEGTMPPELVEVIRRLWKDGGVQACFERAAEYQLNDSASYYLNQLERITDPEYLPSEQDVLRSRVKTTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEVNRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGNNSYDDAGNYIKSQFLDLNMRKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P19087 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S3 | Phosphorylation | Uniprot | |
| S6 | Phosphorylation | Uniprot | |
| K17 | Acetylation | Uniprot | |
| K21 | Acetylation | Uniprot | |
| K35 | Acetylation | Uniprot | |
| S44 | Phosphorylation | Uniprot | |
| K46 | Ubiquitination | Uniprot | |
| K51 | Ubiquitination | Uniprot | |
| Y95 | Phosphorylation | Uniprot | |
| K192 | Ubiquitination | Uniprot | |
| S206 | Phosphorylation | Uniprot | |
| K271 | Ubiquitination | Uniprot |
研究背景
Guanine nucleotide-binding proteins (G proteins) are involved as modulators or transducers in various transmembrane signaling systems. Transducin is an amplifier and one of the transducers of a visual impulse that performs the coupling between rhodopsin and cGMP-phosphodiesterase.
Cell projection>Cilium>Photoreceptor outer segment. Photoreceptor inner segment.
Note: Localizes mainly in the outer segment in the dark-adapted state, whereas is translocated to the inner part of the photoreceptors in the light-adapted state. During dark-adapted conditions, in the presence of UNC119 mislocalizes from the outer segment to the inner part of rod photoreceptors which leads to decreased photoreceptor damage caused by light.
Retinal rod outer segment.
G proteins are composed of 3 units; alpha, beta and gamma. The alpha chain contains the guanine nucleotide binding site.
Belongs to the G-alpha family. G(i/o/t/z) subfamily.
研究領域
· Organismal Systems > Sensory system > Phototransduction.
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