MARCH3 Antibody - #DF4019
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF4019, RRID:AB_2836379.
折りたたみ／展開
E3 ubiquitin protein ligase MARCH3; E3 ubiquitin-protein ligase MARCH3; FLJ20096; March 3; MARCH III; MARCH-III; March3; MARH3_HUMAN; Membrane associated RING CH protein III; Membrane associated ring finger (C3HC4) 3; Membrane associated ring finger (C3HC4) 3, E3 ubiquitin protein ligase; Membrane associated RING finger protein 3; Membrane-associated RING finger protein 3; Membrane-associated RING-CH protein III; MGC48332; RING finger protein 173; RNF173;
免疫原
A synthesized peptide derived from human MARCH3, corresponding to a region within the internal amino acids.
- Q86UD3 MARH3_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTTSRCSHLPEVLPDCTSSAAPVVKTVEDCGSLVNGQPQYVMQVSAKDGQLLSTVVRTLATQSPFNDRPMCRICHEGSSQEDLLSPCECTGTLGTIHRSCLEHWLSSSNTSYCELCHFRFAVERKPRPLVEWLRNPGPQHEKRTLFGDMVCFLFITPLATISGWLCLRGAVDHLHFSSRLEAVGLIALTVALFTIYLFWTLVSFRYHCRLYNEWRRTNQRVILLIPKSVNVPSNQPSLLGLHSVKRNSKETVV
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
E3 ubiquitin-protein ligase which may be involved in endosomal trafficking. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfer the ubiquitin to targeted substrates.
Cytoplasmic vesicle membrane>Multi-pass membrane protein. Early endosome membrane>Multi-pass membrane protein.
The RING-CH-type zinc finger domain is required for E3 ligase activity.
Restrictive clause
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For Research Use Only.
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