DHODH Antibody - #DF3991
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3991, RRID:AB_2836351.
折りたたみ／展開
DHOdehase; Dhodh; Dihydroorotate dehydrogenase (quinone); Dihydroorotate dehydrogenase; Dihydroorotate dehydrogenase mitochondrial; Dihydroorotate oxidase; Human complement of yeast URA1; mitochondrial; POADS; PYRD_HUMAN; URA1;
免疫原
- Q02127 PYRD_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAWRHLKKRAQDAVIILGGGGLLFASYLMATGDERFYAEHLMPTLQGLLDPESAHRLAVRFTSLGLLPRARFQDSDMLEVRVLGHKFRNPVGIAAGFDKHGEAVDGLYKMGFGFVEIGSVTPKPQEGNPRPRVFRLPEDQAVINRYGFNSHGLSVVEHRLRARQQKQAKLTEDGLPLGVNLGKNKTSVDAAEDYAEGVRVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPDLTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSGKPLRDLSTQTIREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTFWGPPVVGKVKRELEALLKEQGFGGVTDAIGADHRR
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q02127 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T62 | Phosphorylation | Uniprot | |
| S63 | Phosphorylation | Uniprot | |
| K86 | Ubiquitination | Uniprot | |
| K99 | Ubiquitination | Uniprot | |
| T121 | Phosphorylation | Uniprot | |
| Y146 | Phosphorylation | Uniprot | |
| K169 | Ubiquitination | Uniprot | |
| K183 | Ubiquitination | Uniprot | |
| K185 | Ubiquitination | Uniprot | |
| Y194 | Phosphorylation | Uniprot | |
| S214 | Phosphorylation | Uniprot | |
| T217 | Phosphorylation | Uniprot | |
| K226 | Ubiquitination | Uniprot | |
| K235 | Ubiquitination | Uniprot | |
| K254 | Ubiquitination | Uniprot | |
| K264 | Ubiquitination | Uniprot | |
| K306 | Ubiquitination | Uniprot | |
| K344 | Ubiquitination | Uniprot | |
| Y355 | Phosphorylation | Uniprot | |
| T356 | Phosphorylation | Uniprot | |
| T359 | Phosphorylation | Uniprot | |
| K378 | Ubiquitination | Uniprot |
研究背景
Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor.
The uncleaved transit peptide is required for mitochondrial targeting and proper membrane integration.
Mitochondrion inner membrane>Single-pass membrane protein.
Monomer.
Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
研究領域
· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.
· Metabolism > Global and overview maps > Metabolic pathways.
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