製品: NT5C1A Antibody
カタログ: DF3978
タンパク質の説明: Rabbit polyclonal antibody to NT5C1A
アプリケーション: WB IF/ICC
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Rabbit, Dog
分子量: 41 KD; 41kD(Calculated).
ユニプロット: Q9BXI3
RRID: AB_2836338

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(91%), Bovine(91%), Horse(100%), Sheep(91%), Rabbit(91%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
NT5C1A Antibody detects endogenous levels of total NT5C1A.
RRID:
AB_2836338
引用形式: Affinity Biosciences Cat# DF3978, RRID:AB_2836338.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

5' nucleotidase cytosolic IA; 5NT1A_HUMAN; AMP specific 5' NT; CN I; CN IA; cN-I; cN-IA; CN1; cN1A; cNI; cNIA; Cytosolic 5' nucleotidase 1A; Cytosolic 5' nucleotidase IA; Cytosolic 5' nucleotidase type 1A; Cytosolic 5''-nucleotidase 1A; Cytosolic 5''-nucleotidase IA; MGC119199; MGC119201; NT5C1A; nucleotidase, 5-prime, cytosolic, IA;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
Q9BXI3 5NT1A_HUMAN:

Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.

タンパク質配列:
MEPGQPREPQEPREPGPGAETAAAPVWEEAKIFYDNLAPKKKPKSPKPQNAVTIAVSSRALFRMDEEQQIYTEQGVEEYVRYQLEHENEPFSPGPAFPFVKALEAVNRRLRELYPDSEDVFDIVLMTNNHAQVGVRLINSINHYDLFIERFCMTGGNSPICYLKAYHTNLYLSADAEKVREAIDEGIAAATIFSPSRDVVVSQSQLRVAFDGDAVLFSDESERIVKAHGLDRFFEHEKAHENKPLAQGPLKGFLEALGRLQKKFYSKGLRLECPIRTYLVTARSAASSGARALKTLRSWGLETDEALFLAGAPKGPLLEKIRPHIFFDDQMFHVAGAQEMGTVAAHVPYGVAQTPRRTAPAKQAPSAQ

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Horse
100
Dog
100
Pig
91
Bovine
91
Sheep
91
Rabbit
91
Chicken
73
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9BXI3 基板として

Site PTM Type Enzyme
K31 Acetylation
Y34 Phosphorylation
S57 Phosphorylation
S58 Phosphorylation
Y79 Phosphorylation
Y265 Phosphorylation
S266 Phosphorylation
K314 Acetylation

研究背景

機能:

Dephosphorylates the 5' and 2'(3')-phosphates of deoxyribonucleotides and has a broad substrate specificity. Helps to regulate adenosine levels in heart during ischemia and hypoxia.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Highly expressed in skeletal muscle. Detected at intermediate levels in heart, brain, kidney and pancreas.

タンパク質ファミリー:

Belongs to the 5'-nucleotidase type 3 family.

研究領域

· Metabolism > Nucleotide metabolism > Purine metabolism.

· Metabolism > Nucleotide metabolism > Pyrimidine metabolism.

· Metabolism > Metabolism of cofactors and vitamins > Nicotinate and nicotinamide metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

Restrictive clause

 

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For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.