製品: CST11 Antibody
カタログ: DF3975
タンパク質の説明: Rabbit polyclonal antibody to CST11
アプリケーション: WB IF/ICC
反応性: Human
分子量: 17 KD(Observed); 17kD(Calculated).
ユニプロット: Q9H112
RRID: AB_2836335

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Polyclonal
特異性:
CST11 Antibody detects endogenous levels of total CST11.
RRID:
AB_2836335
引用形式: Affinity Biosciences Cat# DF3975, RRID:AB_2836335.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Cst11; CST11_HUMAN; CST8L; cystatin 11; cystatin related epididymal specific protein; Cystatin-11; dJ322G13.6; SC13; SC13delta;

免疫原

免疫原:

A synthesized peptide derived from human CST11, corresponding to a region within the internal amino acids.

Uniprot:
遺伝子(ID):
発現特異性:
Q9H112 CST11_HUMAN:

Detected in the epithelium and lumen of the epididymis, and in sperm (at protein level).

タンパク質配列:
MMAEPWQALQLLLAILLTLMALPYQARKKTFLSVHEVMAVENYAKDSLQWITDQYNKESDDKYHFRIFRVLKVQRQVTDHLEYHLNVEMQWTTCQKPETTNCVPQERELHKQVNCFFSVFAVPWFEQYKILNKSCSSD

研究背景

機能:

Has antibacterial activity against the Gram-negative bacteria E.coli. May play a role in sperm maturation and fertilization.

細胞の位置付け:

Secreted.
Note: Probably secreted into the epididymis lumen, where it localizes to the outer surface of sperm. Specifically localizes to the postacrosomal and tail regions of sperm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Detected in the epithelium and lumen of the epididymis, and in sperm (at protein level).

タンパク質ファミリー:

Belongs to the cystatin family.

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