ST6GAL1 Antibody - #DF3950
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製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3950, RRID:AB_2836303.
折りたたみ／展開
6 sialyltransferase; 6-sialyltransferase 1; 6-ST 1; Alpha 2; Alpha 2,6 ST 1; Alpha 2,6 ST; B cell antigen CD75; B-cell antigen CD75; Beta galactoside alpha 2,6 sialyltransferase 1; Beta-galactoside alpha-2; CMP N acetylneuraminate beta galactosamide alpha 2,6 sialyltransferase 1; CMP-N-acetylneuraminate-beta-galactosamide-alpha-2; MGC48859; Sialyltransferase 1 (beta galactoside alpha 2,6 sialyltransferase); Sialyltransferase 1; SIAT1; SIAT1_HUMAN; ST6 beta galactosamide alpha 2,6 sialyltranferase 1; ST6Gal I; ST6GAL1; ST6GalI; ST6N;
免疫原
- P15907 SIAT1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MIHTNLKKKFSCCVLVFLLFAVICVWKEKKKGSYYDSFKLQTKEFQVLKSLGKLAMGSDSQSVSSSSTQDPHRGRQTLGSLRGLAKAKPEASFQVWNKDSSSKNLIPRLQKIWKNYLSMNKYKVSYKGPGPGIKFSAEALRCHLRDHVNVSMVEVTDFPFNTSEWEGYLPKESIRTKAGPWGRCAVVSSAGSLKSSQLGREIDDHDAVLRFNGAPTANFQQDVGTKTTIRLMNSQLVTTEKRFLKDSLYNEGILIVWDPSVYHSDIPKWYQNPDYNFFNNYKTYRKLHPNQPFYILKPQMPWELWDILQEISPEEIQPNPPSSGMLGIIIMMTLCDQVDIYEFLPSKRKTDVCYYYQKFFDSACTMGAYHPLLYEKNLVKHLNQGTDEDIYLLGKATLPGFRTIHC
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - P15907 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| T68 | O-Glycosylation | Uniprot | |
| T77 | Phosphorylation | Uniprot | |
| S80 | Phosphorylation | Uniprot | |
| S92 | Phosphorylation | Uniprot | |
| N149 | N-Glycosylation | Uniprot | |
| N161 | N-Glycosylation | Uniprot | |
| K177 | Ubiquitination | Uniprot | |
| K194 | Ubiquitination | Uniprot | |
| K226 | Ubiquitination | Uniprot | |
| K241 | Ubiquitination | Uniprot | |
| Y369 | Phosphorylation | Uniprot | |
| K380 | Ubiquitination | Uniprot |
研究背景
Transfers sialic acid from CMP-sialic acid to galactose-containing acceptor substrates.
The soluble form derives from the membrane form by proteolytic processing.
The HB-6, CDW75, and CD76 differentiation antigens are cell-surface carbohydrate determinants generated by this enzyme.
N-glycosylated.
Golgi apparatus>Golgi stack membrane>Single-pass type II membrane protein. Secreted.
Note: Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
Monomer and homodimer.
Belongs to the glycosyltransferase 29 family.
研究領域
· Metabolism > Glycan biosynthesis and metabolism > N-Glycan biosynthesis.
· Metabolism > Glycan biosynthesis and metabolism > Other types of O-glycan biosynthesis.
· Metabolism > Global and overview maps > Metabolic pathways.
参考文献
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