製品: CGREF1 Antibody
カタログ: DF3912
タンパク質の説明: Rabbit polyclonal antibody to CGREF1
アプリケーション: WB IHC IF/ICC
反応性: Human, Rat
分子量: 31 KD(Observed); 33kD(Calculated).
ユニプロット: Q99674
RRID: AB_2836265

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 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Rat
クローナリティ:
Polyclonal
特異性:
CGREF1 Antibody detects endogenous levels of total CGREF1.
RRID:
AB_2836265
引用形式: Affinity Biosciences Cat# DF3912, RRID:AB_2836265.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin.
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Cell growth regulator with EF hand domain 1; Cell growth regulator with EF hand domain protein 1; Cell growth regulatory gene 11; Cell growth regulatory gene 11 protein; CGR 11; CGR11; CGRE1_HUMAN; CGREF 1; CGREF1; Hydrophobestin;

免疫原

免疫原:

A synthesized peptide derived from human CGREF1, corresponding to a region within C-terminal amino acids.

Uniprot:
遺伝子(ID):
タンパク質配列:
MLPLTMTVLILLLLPTGQAAPKDGVTRPDSEVQHQLLPNPFQPGQEQLGLLQSYLKGLGRTEVQLEHLSREQVLLYLFALHDYDQSGQLDGLELLSMLTAALAPGAANSPTTNPVILIVDKVLETQDLNGDGLMTPAELINFPGVALRHVEPGEPLAPSPQEPQAVGRQSLLAKSPLRQETQEAPGPREEAKGQVEARRESLDPVQEPGGQAEADGDVPGPRGEAEGQAEAKGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEAEGDAPGPRGEAGGQAEARENGEEAKELPGETLESKNTQNDFEVHIVQVENDEI

研究背景

機能:

Mediates cell-cell adhesion in a calcium-dependent manner (By similarity). Able to inhibit growth in several cell lines.

PTMs:

Probably digested extracellularly by an unknown serine protease generating extremely hydrophobic bioactive peptides.

細胞の位置付け:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Both EF-hands are required for function.

Restrictive clause

 

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