製品: CA3 Antibody
カタログ: DF3889
タンパク質の説明: Rabbit polyclonal antibody to CA3
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Horse, Rabbit, Dog
分子量: 38 KD; 30kD(Calculated).
ユニプロット: P07451
RRID: AB_2836242

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(92%), Horse(92%), Rabbit(92%), Dog(100%)
クローナリティ:
Polyclonal
特異性:
CA3 Antibody detects endogenous levels of total CA3.
RRID:
AB_2836242
引用形式: Affinity Biosciences Cat# DF3889, RRID:AB_2836242.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

CA III; CA-III; Ca3; CAH3_HUMAN; CAIII; Car3; Carbonate dehydratase III; Carbonic anhydrase 3; Carbonic anhydrase III; Carbonic anhydrase III muscle specific; EC 4.2.1.1; Epididymis secretory sperm binding protein Li 167mP; HEL S 167mP;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
P07451 CAH3_HUMAN:

Muscle specific.

タンパク質配列:
MAKEWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKTILNNGKTCRVVFDDTYDRSMLRGGPLPGPYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELHLVHWNPKYNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKFDPSCLFPACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEPPVPLVSNWRPPQPINNRVVRASFK

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Dog
100
Pig
92
Horse
92
Rabbit
92
Bovine
75
Sheep
75
Xenopus
67
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - P07451 基板として

Site PTM Type Enzyme
S9 Phosphorylation
S48 Phosphorylation
S50 Phosphorylation
C66 S-Nitrosylation
Y74 Phosphorylation
S99 Phosphorylation
S100 Phosphorylation
Y114 Phosphorylation
K126 Acetylation
Y127 Phosphorylation
T129 Phosphorylation
T216 Phosphorylation
S242 Phosphorylation

研究背景

機能:

Reversible hydration of carbon dioxide.

PTMs:

S-glutathionylated in hepatocytes under oxidative stress.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Muscle specific.

タンパク質ファミリー:

Belongs to the alpha-carbonic anhydrase family.

研究領域

· Metabolism > Energy metabolism > Nitrogen metabolism.

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