製品: BRP44L Antibody
カタログ: DF3852
タンパク質の説明: Rabbit polyclonal antibody to BRP44L
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse, Rat
予測: Pig, Zebrafish, Bovine, Horse, Sheep, Chicken, Xenopus
分子量: 12 KD; 12kD(Calculated).
ユニプロット: Q9Y5U8
RRID: AB_2836209

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 100ul $280 在庫あり
 200ul $350 在庫あり

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse,Rat
予測:
Pig(100%), Zebrafish(80%), Bovine(100%), Horse(100%), Sheep(100%), Chicken(100%), Xenopus(100%)
クローナリティ:
Polyclonal
特異性:
BRP44L Antibody detects endogenous levels of total BRP44L.
RRID:
AB_2836209
引用形式: Affinity Biosciences Cat# DF3852, RRID:AB_2836209.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

Apoptosis regulating basic protein; Brain protein 44 like protein; CGI 129; CGI129; dJ68L15.3; HSPC040; HSPC040 protein; Mitochondrial pyruvate carrier 1; MPC1; MPYCD; PNAS 115; PNAS115; pyruvate carrier, Mitochondrial, 1;

免疫原

免疫原:

A synthesized peptide derived from human BRP44L, corresponding to a region within the internal amino acids.

Uniprot:
遺伝子(ID):
タンパク質配列:
MAGALVRKAADYVRSKDFRDYLMSTHFWGPVANWGLPIAAINDMKKSPEIISGRMTFALCCYSLTFMRFAYKVQPRNWLLFACHATNEVAQLIQGGRLIKHEMTKTASA

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
100
Horse
100
Bovine
100
Sheep
100
Xenopus
100
Chicken
100
Zebrafish
80
Dog
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

研究背景

機能:

Mediates the uptake of pyruvate into mitochondria.

細胞の位置付け:

Mitochondrion inner membrane>Multi-pass membrane protein.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family.

参考文献

1). Type 2 diabetes mellitus facilitates endometrial hyperplasia progression by activating the proliferative function of mucin O-glycosylating enzyme GALNT2. Biomedicine & Pharmacotherapy, 2020 (PubMed: 33152927) [IF=6.9]

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