| 製品: | APOA4 Antibody |
| カタログ: | DF3782 |
| タンパク質の説明: | Rabbit polyclonal antibody to APOA4 |
| アプリケーション: | WB |
| 反応性: | Human |
| 分子量: | 45 KD(Observed); 45kD(Calculated). |
| ユニプロット: | P06727 |
| RRID: | AB_2836139 |
Control Products
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3782, RRID:AB_2836139.
折りたたみ／展開
Apo AIV; APOA 4; ApoA IV; APOA4; Apolipoprotein A IV; Apolipoprotein A4; MGC142154; MGC142156;
免疫原
A synthesized peptide derived from human APOA4, corresponding to a region within C-terminal amino acids.
- P06727 APOA4_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MFLKAVVLTLALVAVAGARAEVSADQVATVMWDYFSQLSNNAKEAVEHLQKSELTQQLNALFQDKLGEVNTYAGDLQKKLVPFATELHERLAKDSEKLKEEIGKELEELRARLLPHANEVSQKIGDNLRELQQRLEPYADQLRTQVNTQAEQLRRQLTPYAQRMERVLRENADSLQASLRPHADELKAKIDQNVEELKGRLTPYADEFKVKIDQTVEELRRSLAPYAQDTQEKLNHQLEGLTFQMKKNAEELKARISASAEELRQRLAPLAEDVRGNLRGNTEGLQKSLAELGGHLDQQVEEFRRRVEPYGENFNKALVQQMEQLRQKLGPHAGDVEGHLSFLEKDLRDKVNSFFSTFKEKESQDKTLSLPELEQQQEQQQEQQQEQVQMLAPLES
研究背景
May have a role in chylomicrons and VLDL secretion and catabolism. Required for efficient activation of lipoprotein lipase by ApoC-II; potent activator of LCAT. Apoa-IV is a major component of HDL and chylomicrons.
Phosphorylation sites are present in the extracellular medium.
Secreted.
Synthesized primarily in the intestine and secreted in plasma.
Nine of the thirteen 22-amino acid tandem repeats (each 22-mer is actually a tandem array of two, A and B, related 11-mers) occurring in this sequence are predicted to be highly alpha-helical, and many of these helices are amphipathic. They may therefore serve as lipid-binding domains with lecithin:cholesterol acyltransferase (LCAT) activating abilities.
Belongs to the apolipoprotein A1/A4/E family.
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