製品: PGLS Antibody
カタログ: DF3715
タンパク質の説明: Rabbit polyclonal antibody to PGLS
アプリケーション: WB IHC IF/ICC
反応性: Human, Mouse
予測: Pig, Bovine, Horse, Sheep, Dog, Chicken
分子量: 30 KD; 28kD(Calculated).
ユニプロット: O95336
RRID: AB_2836079

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製品説明

ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IHC 1:50-1:200, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human,Mouse
予測:
Pig(91%), Bovine(91%), Horse(91%), Sheep(91%), Dog(91%), Chicken(82%)
クローナリティ:
Polyclonal
特異性:
PGLS Antibody detects endogenous levels of total PGLS.
RRID:
AB_2836079
引用形式: Affinity Biosciences Cat# DF3715, RRID:AB_2836079.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

6 phosphogluconolactonase; 6PGL;

免疫原

免疫原:

A synthesized peptide derived from human PGLS, corresponding to a region within C-terminal amino acids.

Uniprot:
遺伝子(ID):
タンパク質配列:
MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGARARFALGLSGGSLVSMLARELPAAVAPAGPASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLPIPESQVITINPELPVEEAAEDYAKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPKPPPQRVTLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFLDEAAARLLTVPFEKHSTL

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
91
Horse
91
Bovine
91
Sheep
91
Dog
91
Chicken
82
Xenopus
0
Zebrafish
0
Rabbit
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - O95336 基板として

Site PTM Type Enzyme
A2 Acetylation
S46 Phosphorylation
S49 Phosphorylation
R81 Methylation
T91 Phosphorylation
Y92 Phosphorylation
K128 Ubiquitination
S178 Phosphorylation
K180 Acetylation
T204 Phosphorylation
K235 Ubiquitination
T249 Phosphorylation
K254 Ubiquitination
T257 Phosphorylation

研究背景

機能:

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

細胞の位置付け:

Cytoplasm.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 6-phosphogluconolactonase subfamily.

研究領域

· Metabolism > Carbohydrate metabolism > Pentose phosphate pathway.

· Metabolism > Global and overview maps > Metabolic pathways.

· Metabolism > Global and overview maps > Carbon metabolism.

Restrictive clause

 

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For Research Use Only.
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