MUTYH Antibody - #AF0379
| 製品: | MUTYH Antibody |
| カタログ: | AF0379 |
| タンパク質の説明: | Rabbit polyclonal antibody to MUTYH |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse, Rat |
| 予測: | Zebrafish, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 60kDa; 60kD(Calculated). |
| ユニプロット: | Q9UIF7 |
| RRID: | AB_2833538 |
製品説明
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# AF0379, RRID:AB_2833538.
折りたたみ／展開
A/G specific adenine DNA glycosylase; A/G-specific adenine DNA glycosylase; Adenine DNA glycosylase; CYP2C; hMYH; MGC4416; MutY (E. coli) homolog; MutY homolog (E. coli); MutY homolog; MutY, E. coli, homolog of; Mutyh; MUTYH_HUMAN; MYH; rMYH;
免疫原
- Q9UIF7 MUTYH_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTPLVSRLSRLWAIMRKPRAAVGSGHRKQAASQEGRQKHAKNNSQAKPSACDGMIAECPGAPAGLARQPEEVVLQASVSSYHLFRDVAEVTAFRGSLLSWYDQEKRDLPWRRRAEDEMDLDRRAYAVWVSEVMLQQTQVATVINYYTGWMQKWPTLQDLASASLEEVNQLWAGLGYYSRGRRLQEGARKVVEELGGHMPRTAETLQQLLPGVGRYTAGAIASIAFGQATGVVDGNVARVLCRVRAIGADPSSTLVSQQLWGLAQQLVDPARPGDFNQAAMELGATVCTPQRPLCSQCPVESLCRARQRVEQEQLLASGSLSGSPDVEECAPNTGQCHLCLPPSEPWDQTLGVVNFPRKASRKPPREESSATCVLEQPGALGAQILLVQRPNSGLLAGLWEFPSVTWEPSEQLQRKALLQELQRWAGPLPATHLRHLGEVVHTFSHIKLTYQVYGLALEGQTPVTTVPPGARWLTQEEFHTAAVSTAMKKVFRVYQGQQPGTCMGSKRSQVSSPCSRKKPRMGQQVLDNFFRSHISTDAHSLNSAAQ
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9UIF7 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S6 | Phosphorylation | Uniprot | |
| S9 | Phosphorylation | Uniprot | |
| S24 | Phosphorylation | Uniprot | |
| K105 | Ubiquitination | Uniprot | |
| K189 | Ubiquitination | Uniprot | |
| S360 | Phosphorylation | Uniprot | |
| K415 | Ubiquitination | Uniprot | |
| Y494 | Phosphorylation | Uniprot | |
| S505 | Phosphorylation | Uniprot | |
| K506 | Ubiquitination | Uniprot | |
| S512 | Phosphorylation | Uniprot | |
| S535 | Phosphorylation | Uniprot |
研究背景
Involved in oxidative DNA damage repair. Initiates repair of A*oxoG to C*G by removing the inappropriately paired adenine base from the DNA backbone. Possesses both adenine and 2-OH-A DNA glycosylase activities.
Nucleus. Mitochondrion.
Belongs to the Nth/MutY family.
研究領域
· Genetic Information Processing > Replication and repair > Base excision repair.
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