製品: CHKB Antibody
カタログ: DF3477
タンパク質の説明: Rabbit polyclonal antibody to CHKB
アプリケーション: WB IHC IF/ICC
反応性: Human
予測: Pig, Bovine, Rabbit, Dog
分子量: 45 KD; 45kD(Calculated).
ユニプロット: Q9Y259
RRID: AB_2835840

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製品説明

ソース:
Rabbit
アプリケーション:
IHC 1:50-1:200, WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
予測:
Pig(91%), Bovine(91%), Rabbit(82%), Dog(91%)
クローナリティ:
Polyclonal
特異性:
CHKB Antibody detects endogenous levels of total CHKB.
RRID:
AB_2835840
引用形式: Affinity Biosciences Cat# DF3477, RRID:AB_2835840.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ/展開

CHETK; Chetk-beta; Chkb; Chkb choline kinase beta; Chkb protein; CHKB_HUMAN; CHKL; Choline kinase beta; Choline kinase-like; Choline kinase-like protein; Choline/ethanolamine kinase; choline/ethanolamine kinase beta; Choline/ethanolamine kinase, beta; CK; CK/EK; CK/EK-beta; CKB; CKEKB; EK; EKB; Ethanolamine kinase; Ethanolamine kinase beta; Ethanolamine kinase, beta; MDCMC;

免疫原

免疫原:
Uniprot:
遺伝子(ID):
タンパク質配列:
MAAEATAVAGSGAVGGCLAKDGLQQSKCPDTTPKRRRASSLSRDAERRAYQWCREYLGGAWRRVQPEELRVYPVSGGLSNLLFRCSLPDHLPSVGEEPREVLLRLYGAILQGVDSLVLESVMFAILAERSLGPQLYGVFPEGRLEQYIPSRPLKTQELREPVLSAAIATKMAQFHGMEMPFTKEPHWLFGTMERYLKQIQDLPPTGLPEMNLLEMYSLKDEMGNLRKLLESTPSPVVFCHNDIQEGNILLLSEPENADSLMLVDFEYSSYNYRGFDIGNHFCEWVYDYTHEEWPFYKARPTDYPTQEQQLHFIRHYLAEAKKGETLSQEEQRKLEEDLLVEVSRYALASHFFWGLWSILQASMSTIEFGYLDYAQSRFQFYFQQKGQLTSVHSSS

種類予測

種類予測:

Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.

Species
Results
Score
Pig
91
Bovine
91
Dog
91
Rabbit
82
Horse
73
Sheep
73
Xenopus
0
Zebrafish
0
Chicken
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence

PTMs - Q9Y259 基板として

Site PTM Type Enzyme
A2 Acetylation
S39 Phosphorylation
S40 Phosphorylation
S42 Phosphorylation
Y72 Phosphorylation
S75 Phosphorylation
S79 Phosphorylation
K321 Ubiquitination
Y381 Phosphorylation
S394 Phosphorylation

研究背景

機能:

Has a key role in phospholipid metabolism, and catalyzes the first step of phosphatidylethanolamine and phosphatidylcholine biosynthesis.

サブユニット構造:

Homodimer, and heterodimer with CHKA.

タンパク質ファミリー:

Belongs to the choline/ethanolamine kinase family.

研究領域

· Human Diseases > Cancers: Overview > Choline metabolism in cancer.   (View pathway)

· Metabolism > Lipid metabolism > Glycerophospholipid metabolism.

· Metabolism > Global and overview maps > Metabolic pathways.

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