UTP14A Antibody - #DF3418
(1)
(2)
| 製品: | UTP14A Antibody |
| カタログ: | DF3418 |
| タンパク質の説明: | Rabbit polyclonal antibody to UTP14A |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human, Mouse |
| 予測: | Pig, Horse, Dog |
| 分子量: | 85 KD; 88kD(Calculated). |
| ユニプロット: | Q9BVJ6 |
| RRID: | AB_2835800 |
製品説明
ソース:
Rabbit
アプリケーション:
WB 1:500-1:1000, IF/ICC 1:100-1:500
*The optimal dilutions should be determined by the end user.
*Tips:
*The optimal dilutions should be determined by the end user.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human,Mouse
予測:
Pig(88%), Horse(88%), Dog(88%)
クローナリティ:
Polyclonal
特異性:
UTP14A Antibody detects endogenous levels of total UTP14A.
RRID:
AB_2835800
引用形式: Affinity Biosciences Cat# DF3418, RRID:AB_2835800.
引用形式: Affinity Biosciences Cat# DF3418, RRID:AB_2835800.
コンジュゲート:
Unconjugated.
精製:
The antiserum was purified by peptide affinity chromatography using SulfoLink™ Coupling Resin (Thermo Fisher Scientific).
保存:
Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
Antigen NY CO 16; KIAA0266; SDCCAG16; Serologically defined colon cancer antigen 16; U3 small nucleolar RNA associated protein 14 homolog A; UTP14;
免疫原
免疫原:
Uniprot:
遺伝子(ID):
発現特異性:
タンパク質配列:
- Q9BVJ6 UT14A_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MTANRLAESLLALSQQEELADLPKDYLLSESEDEGDNDGERKHQKLLEAISSLDGKNRRKLAERSEASLKVSEFNVSSEGSGEKLVLADLLEPVKTSSSLATVKKQLSRVKSKKTVELPLNKEEIERIHREVAFNKTAQVLSKWDPVVLKNRQAEQLVFPLEKEEPAIAPIEHVLSGWKARTPLEQEIFNLLHKNKQPVTDPLLTPVEKASLRAMSLEEAKMRRAELQRARALQSYYEAKARREKKIKSKKYHKVVKKGKAKKALKEFEQLRKVNPAAALEELEKIEKARMMERMSLKHQNSGKWAKSKAIMAKYDLEARQAMQEQLSKNKELTQKLQVASESEEEEGGTEDVEELLVPDVVNEVQMNADGPNPWMLRSCTSDTKEAATQEDPEQLPELEAHGVSESEGEERPVAEEEILLREFEERRSLRKRSELSQDAEPAGSQETKDSGSQEVLSELRVLSQKLKENHQSRKQKASSEGTIPQVQREEPAPEEEEPLLLQRPERVQTLEELEELGKEECFQNKELPRPVLEGQQSERTPNNRPDAPKEKKKKEQMIDLQNLLTTQSPSVKSLAVPTIEELEDEEERNHRQMIKEAFAGDDVIRDFLKEKREAVEASKPKDVDLTLPGWGEWGGVGLKPSAKKRRRFLIKAPEGPPRKDKNLPNVIINEKRNIHAAAHQVRVLPYPFTHHWQFERTIQTPIGSTWNTQRAFQKLTTPKVVTKPGHIINPIKAEDVGYRSSSRSDLSVIQRNPKRITTRHKKQLKKCSVD
種類予測
種類予測:
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
Species
Results
Score
Pig
88
Horse
88
Dog
88
Bovine
75
Rabbit
75
Chicken
67
Sheep
0
Xenopus
0
Zebrafish
0
Model Confidence:
High(score>80) Medium(80>score>50) Low(score<50) No confidence
High(score>80) Medium(80>score>50) Low(score<50) No confidence
PTMs - Q9BVJ6 基板として
| Site | PTM Type | Enzyme | Source |
|---|---|---|---|
| S9 | Phosphorylation | Uniprot | |
| S14 | Phosphorylation | Uniprot | |
| Y26 | Phosphorylation | Uniprot | |
| S29 | Phosphorylation | Uniprot | |
| S31 | Phosphorylation | Uniprot | |
| K45 | Sumoylation | Uniprot | |
| S52 | Phosphorylation | Uniprot | |
| K56 | Acetylation | Uniprot | |
| S65 | Phosphorylation | Uniprot | |
| S77 | Phosphorylation | Uniprot | |
| S78 | Phosphorylation | Uniprot | |
| S81 | Phosphorylation | Uniprot | |
| S99 | Phosphorylation | Uniprot | |
| T102 | Phosphorylation | Uniprot | |
| K136 | Methylation | Uniprot | |
| K143 | Ubiquitination | Uniprot | |
| K179 | Ubiquitination | Uniprot | |
| K194 | Ubiquitination | Uniprot | |
| K196 | Ubiquitination | Uniprot | |
| T205 | Phosphorylation | Uniprot | |
| K288 | Ubiquitination | Uniprot | |
| K298 | Methylation | Uniprot | |
| K307 | Methylation | Uniprot | |
| K309 | Methylation | Uniprot | |
| K314 | Sumoylation | Uniprot | |
| S341 | Phosphorylation | Uniprot | |
| S343 | Phosphorylation | Uniprot | |
| T389 | Phosphorylation | Uniprot | |
| S405 | Phosphorylation | Uniprot | |
| S407 | Phosphorylation | Uniprot | |
| S429 | Phosphorylation | Uniprot | |
| S434 | Phosphorylation | Uniprot | |
| S437 | Phosphorylation | Uniprot | |
| S445 | Phosphorylation | Uniprot | |
| T448 | Phosphorylation | Uniprot | |
| S451 | Phosphorylation | Uniprot | |
| S453 | Phosphorylation | Uniprot | |
| S458 | Phosphorylation | Uniprot | |
| S479 | Phosphorylation | Uniprot | |
| S480 | Phosphorylation | Uniprot | |
| T510 | Phosphorylation | Uniprot | |
| S538 | Phosphorylation | Uniprot | |
| T541 | Phosphorylation | Uniprot | |
| S569 | Phosphorylation | Uniprot | |
| S571 | Phosphorylation | Uniprot | |
| K620 | Sumoylation | Uniprot | |
| K640 | Ubiquitination | Uniprot | |
| S642 | Phosphorylation | Uniprot | |
| K652 | Methylation | Uniprot | |
| K662 | Ubiquitination | Uniprot | |
| K672 | Ubiquitination | Uniprot | |
| T701 | Phosphorylation | Uniprot | |
| K733 | Acetylation | Uniprot | |
| K733 | Sumoylation | Uniprot | |
| S741 | Phosphorylation | Uniprot | |
| S743 | Phosphorylation | Uniprot | |
| S748 | Phosphorylation | Uniprot |
研究背景
機能:
May be required for ribosome biogenesis.
PTMs:
Citrullinated by PADI4.
細胞の位置付け:
Nucleus>Nucleolus.
組織特異性:
Ubiquitously expressed.
タンパク質ファミリー:
Belongs to the UTP14 family.
研究領域
· Genetic Information Processing > Translation > Ribosome biogenesis in eukaryotes.
参考文献
1). Overexpression of U three protein 14a (UTP14a) is associated with poor prognosis of esophageal squamous cell carcinoma. Thoracic Cancer
(PubMed: 31496055)
[IF=2.9]
Application: IHC Species: human Sample: esophageal squamous cell carcinoma (ESCC) and CDM tissues
Figure 1 |IHC staining and Western blot analysis of UTP14a in esophageal squamous cell carcinoma (ESCC) and CDM tissues. (a–d) Negative to strong UTP14a expression in ESCC tissues.
Application: WB Species: human Sample: ESCC and CDM tissue
Figure 1 |IHC staining and Western blot analysis of UTP14a in esophageal squamous cell carcinoma (ESCC) and CDM tissues. (a–d) Negative to strong UTP14a expression in ESCC tissues.(e–f) Negative-to-moderate UTP14a expression in CDM tissues. (h) Western blot analysis of six pairs of ESCC and CDM tissue.
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.