TINF2 Antibody - #DF3415
| 製品: | TINF2 Antibody |
| カタログ: | DF3415 |
| タンパク質の説明: | Rabbit polyclonal antibody to TINF2 |
| アプリケーション: | WB IF/ICC |
| 反応性: | Human |
| 予測: | Pig, Bovine, Horse, Sheep, Rabbit, Dog |
| 分子量: | 53 KD; 50kD(Calculated). |
| ユニプロット: | Q9BSI4 |
| RRID: | AB_2835797 |
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3415, RRID:AB_2835797.
折りたたみ／展開
AW552114; D14Wsu146e; DKCA3; MGC94711; TERF 1 (TRF 1) interacting nuclear factor 2; TERF 1 interacting nuclear factor 2; TERF1 (TRF1) interacting nuclear factor 2; TERF1 interacting nuclear factor 2; TERF1-interacting nuclear factor 2; Tin 2; TIN2; TINF 2; Tinf2; TINF2_HUMAN; TRF 1 interacting nuclear factor 2; TRF1 interacting nuclear factor 2; TRF1-interacting nuclear protein 2;
免疫原
A synthesized peptide derived from human TINF2, corresponding to a region within the internal amino acids.
Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
- Q9BSI4 TINF2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MATPLVAGPAALRFAAAASWQVVRGRCVEHFPRVLEFLRSLRAVAPGLVRYRHHERLCMGLKAKVVVELILQGRPWAQVLKALNHHFPESGPIVRDPKATKQDLRKILEAQETFYQQVKQLSEAPVDLASKLQELEQEYGEPFLAAMEKLLFEYLCQLEKALPTPQAQQLQDVLSWMQPGVSITSSLAWRQYGVDMGWLLPECSVTDSVNLAEPMEQNPPQQQRLALHNPLPKAKPGTHLPQGPSSRTHPEPLAGRHFNLAPLGRRRVQSQWASTRGGHKERPTVMLFPFRNLGSPTQVISKPESKEEHAIYTADLAMGTRAASTGKSKSPCQTLGGRALKENPVDLPATEQKENCLDCYMDPLRLSLLPPRARKPVCPPSLCSSVITIGDLVLDSDEEENGQGEGKESLENYQKTKFDTLIPTLCEYLPPSGHGAIPVSSCDCRDSSRPL
種類予測
Score>80(red) has high confidence and is suggested to be used for WB detection. *The prediction model is mainly based on the alignment of immunogen sequences, the results are for reference only, not as the basis of quality assurance.
High(score>80) Medium(80>score>50) Low(score<50) No confidence
研究背景
Component of the shelterin complex (telosome) that is involved in the regulation of telomere length and protection. Shelterin associates with arrays of double-stranded TTAGGG repeats added by telomerase and protects chromosome ends; without its protective activity, telomeres are no longer hidden from the DNA damage surveillance and chromosome ends are inappropriately processed by DNA repair pathways. Plays a role in shelterin complex assembly. Isoform 1 may have additional role in tethering telomeres to the nuclear matrix.
Nucleus. Chromosome>Telomere.
Note: Associated with telomeres.
Nucleus matrix.
Detected in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.
The TBM domain mediates interaction with TERF1.
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