ORCTL-2 Antibody - #DF3394
製品説明
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
引用形式: Affinity Biosciences Cat# DF3394, RRID:AB_2835776.
折りたたみ／展開
Beckwith Wiedemann syndrome chromosomal region 1 candidate gene A protein; Beckwith Wiedemann syndrome chromosome region 1 candidate A; BWR1A; BWSCR1A; DKFZp667A184; Efflux transporter like protein; HET; Imprinted multi membrane spanning polyspecific transporter related protein 1; IMPT1; ITM; MGC94186; ORCTL 2; ORCTL2; Organic cation transporter like protein 2; OTTMUSP00000030799; OTTMUSP00000030800; p45 Beckwith Wiedemann region 1 A; p45 BWR1A; SLC22A18; SLC22A1L; Solute carrier family 22 member 1 like; TSSC5; TSSC5v; Tumor suppressing STF cDNA 5 protein; Tumor suppressing subchromosomal transferable fragment candidate gene 5 protein;
免疫原
A synthesized peptide derived from human ORCTL-2, corresponding to a region within C-terminal amino acids.
Expressed at high levels in adult and fetal kidney and liver, and adult colon. Expressed in fetal renal proximal tubules (at protein level). Expressed at lower levels in heart, brain and lung.
- Q96BI1 S22AI_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MQGARAPRDQGRSPGRMSALGRSSVILLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYLQTTFGVLQLLGGPVFGRFADQRGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMHTLPAAQMVITDLSAPEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPASTKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDVPRIFLVKVASNCPTGLFMVMFSIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVLLRASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVTDSMLIKAVSTSDTGTMLGLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRKDKVR
研究背景
May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney.
Apical cell membrane>Multi-pass membrane protein.
Note: Localized at the apical membrane surface of renal proximal tubules.
Expressed at high levels in adult and fetal kidney and liver, and adult colon. Expressed in fetal renal proximal tubules (at protein level). Expressed at lower levels in heart, brain and lung.
Belongs to the major facilitator (TC 2.A.1) superfamily. Organic cation transporter (TC 2.A.1.19) family.
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