Prolactin/PRL Recombinant Rabbit mAb - #BF4415

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製品: Prolactin/PRL Recombinant Rabbit mAb
カタログ: BF4415
タンパク質の説明: Rabbit monoclonal antibody to Prolactin/PRL
アプリケーション: WB IHC
反応性: Mouse, Rat
分子量: 23 kDa(Observed); 26kD(Calculated).
ユニプロット: P01236

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製品説明

ソース:
Rabbit IgG
アプリケーション:
WB 1:1000, IHC 1:1000-1:10000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Mouse, Rat
クローナリティ:
Monoclonal [ReFirm23865]
特異性:
Prolactin/PRL Recombinant Rabbit mAb detects endogenous levels of Prolactin/PRL.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Decidual prolactin; GHA1; Growth hormone A1; Lactogenic hormone; Luteotropic hormone; Mammotropin; PRL; Prolactin; Prolactin precursor;

免疫原

免疫原:

A synthetic peptide from human Prolactin

Uniprot:

P01236(PRL_HUMAN) >>Visit HPA database.

遺伝子(ID):
PRL(5617)
タンパク質の説明:
This gene encodes the anterior pituitary hormone prolactin. This secreted hormone is a growth regulator for many tissues,including cells of the immune system. It may also play a role in cell survival by suppressing apoptosis,and it is essential for lactation. Alternative splicing results in multiple transcript variants that encode the same protein.
タンパク質配列:
MNIKGSPWKGSLLLLLVSNLLLCQSVAPLPICPGGAARCQVTLRDLFDRAVVLSHYIHNLSSEMFSEFDKRYTHGRGFITKAINSCHTSSLATPEDKEQAQQMNQKDFLSLIVSILRSWNEPLYHLVTEVRGMQEAPEAILSKAVEIEEQTKRLLEGMELIVSQVHPETKENEIYPVWSGLPSLQMADEESRLSAYYNLLHCLRRDSHKIDNYLKLLKCRIIHNNNC

研究背景

機能:

Prolactin acts primarily on the mammary gland by promoting lactation.

細胞の位置付け:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the somatotropin/prolactin family.

研究領域

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Environmental Information Processing > Signaling molecules and interaction > Neuroactive ligand-receptor interaction.

· Environmental Information Processing > Signal transduction > PI3K-Akt signaling pathway.   (View pathway)

· Environmental Information Processing > Signal transduction > Jak-STAT signaling pathway.   (View pathway)

· Organismal Systems > Endocrine system > Prolactin signaling pathway.   (View pathway)

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