Filamin C Recombinant Rabbit mAb - #BF4166

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製品: Filamin C Recombinant Rabbit mAb
カタログ: BF4166
タンパク質の説明: Rabbit monoclonal antibody to Filamin C
アプリケーション: WB IHC
反応性: Human
分子量: 291 kDa(Observed);
ユニプロット: Q14315

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製品説明

ソース:
Rabbit IgG
アプリケーション:
WB 1:2000-1:20000, IHC 1:100-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human
クローナリティ:
Monoclonal [ReFirm23613]
特異性:
Filamin C Recombinant Rabbit mAb detects endogenous levels of Filamin C.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

ABPA,ABPL,FLN2,MFM5,MPD4,RCM5,CMH26,ABP-280,ABP280A

免疫原

免疫原:

A synthetic peptide from human Filamin C

タンパク質の説明:
This gene encodes one of three related filamin genes,specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain,a C-terminal self-association domain,and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

研究領域

· Cellular Processes > Cellular community - eukaryotes > Focal adhesion.   (View pathway)

· Environmental Information Processing > Signal transduction > MAPK signaling pathway.   (View pathway)

· Human Diseases > Infectious diseases: Bacterial > Salmonella infection.

· Human Diseases > Cancers: Overview > Proteoglycans in cancer.

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