Calretinin Recombinant Rabbit mAb - #BF4088
製品説明
ソース:
Rabbit IgG
アプリケーション:
WB 1:1000, IHC 1:200-1:500, ICC
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human, Mouse, Rat
クローナリティ:
Monoclonal [ReFirm23535]
特異性:
Calretinin Recombinant Rabbit mAb detects endogenous levels of Calretinin.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
29 kDa calbindin; CAB 29; CAB29; CAL 2; CAL2; CALB 2; CALB2; CALB2_HUMAN; Calbindin 2 29kDa; Calbindin 2; Calbindin D29K; Calbindin2; Calretinin; CR;
免疫原
免疫原:
A synthetic peptide from human Calretinin
Uniprot:
遺伝子(ID):
発現特異性:
タンパク質の説明:
This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions,including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability,and is a diagnostic marker for some human diseases,including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants.
タンパク質配列:
- P22676 CALB2_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MAGPQQQPPYLHLAELTASQFLEIWKHFDADGNGYIEGKELENFFQELEKARKGSGMMSKSDNFGEKMKEFMQKYDKNSDGKIEMAELAQILPTEENFLLCFRQHVGSSAEFMEAWRKYDTDRSGYIEANELKGFLSDLLKKANRPYDEPKLQEYTQTILRMFDLNGDGKLGLSEMSRLLPVQENFLLKFQGMKLTSEEFNAIFTFYDKDRSGYIDEHELDALLKDLYEKNKKEMNIQQLTNYRKSVMSLAEAGKLYRKDLEIVLCSEPPM
研究背景
機能:
Calretinin is a calcium-binding protein which is abundant in auditory neurons.
組織特異性:
Brain.
タンパク質ファミリー:
Belongs to the calbindin family.
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For Research Use Only.
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