GSDMD Recombinant Rabbit mAb - #BF4002
製品説明
ソース:
Rabbit IgG
アプリケーション:
WB 1:1000, IHC 1:200-1:1000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Mouse, Rat
クローナリティ:
Monoclonal [ReFirm23449]
特異性:
GSDMD Recombinant Rabbit mAb detects endogenous levels of GSDMD.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
DF5L,M2-4,Dfna5l,GsdmD-1,Gsdmdc1,1810036L03Rik
免疫原
免疫原:
A synthetic peptide from mouse GSDMD
タンパク質の説明:
Enables phospholipid binding activity and wide pore channel activity. Involved in several processes,including defense response to bacterium,positive regulation of interleukin-1 beta production,and protein-containing complex assembly. Acts upstream of or within cellular response to extracellular stimulus. Located in cytosol,extracellular space,and plasma membrane. Part of NLRP3 inflammasome complex. Is expressed in several structures,including gut,liver,lung,metanephros,and spleen. Orthologous to human GSDMD (gasdermin D).
Restrictive clause
Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.
For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.