SCGB1A1 Recombinant Rabbit mAb - #BF3825

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製品: SCGB1A1 Recombinant Rabbit mAb
カタログ: BF3825
タンパク質の説明: Rabbit monoclonal antibody to SCGB1A1
アプリケーション: WB
反応性: Human, Mouse, Rat
分子量: 16 kDa(Observed); 10kD(Calculated).
ユニプロット: P11684

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製品説明

ソース:
Rabbit IgG
アプリケーション:
WB 1:1000-1:3000
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human, Mouse, Rat
クローナリティ:
Monoclonal [ReFirm23272]
特異性:
SCGB1A1 Recombinant Rabbit mAb detects endogenous levels of SCGB1A1.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

Blastokinin; CC10; CC16; CCPBP; CCSP; Clara cell phospholipid binding protein; Clara cell phospholipid-binding protein; Clara cell specific 10 kD protein; Clara cells 10 kDa secretory protein; OTTHUMP00000236107; SCGB1A1; Secretoglobin family 1A member 1; Secretoglobin, family 1A, member 1 (uteroglobin); UG; UGB; UP-1; UP1; Urinary protein 1; Urine protein 1; UTER_HUMAN; Uteroglobin;

免疫原

免疫原:

A synthetic peptide from human SCGB1A1

Uniprot:

P11684(UTER_HUMAN) >>Visit HPA database.

遺伝子(ID):
SCGB1A1(7356)
発現特異性:
P11684 UTER_HUMAN:

Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways).

タンパク質の説明:
This gene encodes a member of the secretoglobin family of small secreted proteins. The encoded protein has been implicated in numerous functions including anti-inflammation,inhibition of phospholipase A2 and the sequestering of hydrophobic ligands. Defects in this gene are associated with a susceptibility to asthma.
タンパク質配列:
MKLAVTLTLVTLALCCSSASAEICPSFQRVIETLLMDTPSSYEAAMELFSPDQDMREAGAQLKKLVDTLPQKPRESIIKLMEKIAQSSLCN

研究背景

機能:

Binds phosphatidylcholine, phosphatidylinositol, polychlorinated biphenyls (PCB) and weakly progesterone, potent inhibitor of phospholipase A2.

細胞の位置付け:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
組織特異性:

Clara cells (nonciliated cells of the surface epithelium of the pulmonary airways).

タンパク質ファミリー:

Belongs to the secretoglobin family.

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