PPBP Recombinant Rabbit mAb - #BF3692

Copy Info
製品: PPBP Recombinant Rabbit mAb
カタログ: BF3692
タンパク質の説明: Rabbit monoclonal antibody to PPBP
アプリケーション: WB IHC
反応性: Human, Rat
分子量: 11 kDa(Observed); 11kD(Calculated).
ユニプロット: P02776

類似製品を見る>>

   サイズ 価格 在庫状況
 100ul $280 在庫あり

リードタイム: 当日配達

For pricing and ordering contact:
お問い合わせ先
Control Products
関連ダウンロード
MSDS
説明書
COA
プロトコル
WB Handbook
IHC Protocol
IF/ICC Protocol

製品説明

ソース:
Rabbit IgG
アプリケーション:
WB 1:1000-1:5000, IHC 1:100-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:

WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.

反応性:
Human, Rat
クローナリティ:
Monoclonal [ReFirm23139]
特異性:
PPBP Recombinant Rabbit mAb detects endogenous levels of PPBP.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:

折りたたみ／展開

C-X-C motif chemokine 4;Chemokine (C X C motif) ligand 4;Chemokine (CXC motif) ligand 4;chemokine ligand 4;CXCL 4;CXCL4;Iroplact;MGC138298;Oncostatin A;Oncostatin-A;OncostatinA;PF 4;PF-4;PF4;Pf4a;Platelet factor 4;PLF4_HUMAN;SCYB 4;SCYB4;short form;Small inducible cytokine subfamily B;Small inducible cytokine subfamily member 4 antibody

免疫原

免疫原:

A synthetic peptide from human PPBP

Uniprot:

P02776(PLF4_HUMAN) >>Visit HPA database.

遺伝子(ID):
PF4(5196)
タンパク質の説明:
This gene encodes a member of the CXC chemokine family. This chemokine is released from the alpha granules of activated platelets in the form of a homotetramer which has high affinity for heparin and is involved in platelet aggregation. This protein is chemotactic for numerous other cell type and also functions as an inhibitor of hematopoiesis,angiogenesis and T-cell function. The protein also exhibits antimicrobial activity against Plasmodium falciparum.
タンパク質配列:
MSSAAGFCASRPGLLFLGLLLLPLVVAFASAEAEEDGDLQCLCVKTTSQVRPRHITSLEVIKAGPHCPTAQLIATLKNGRKICLDLQAPLYKKIIKKLLES

研究背景

機能:

Released during platelet aggregation. Neutralizes the anticoagulant effect of heparin because it binds more strongly to heparin than to the chondroitin-4-sulfate chains of the carrier molecule. Chemotactic for neutrophils and monocytes. Inhibits endothelial cell proliferation, the short form is a more potent inhibitor than the longer form.

細胞の位置付け:

Secreted.

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionSubcellular location
タンパク質ファミリー:

Belongs to the intercrine alpha (chemokine CxC) family.

研究領域

· Environmental Information Processing > Signaling molecules and interaction > Cytokine-cytokine receptor interaction.   (View pathway)

· Organismal Systems > Immune system > Chemokine signaling pathway.   (View pathway)

Restrictive clause

 

Affinity Biosciences tests all products strictly. Citations are provided as a resource for additional applications that have not been validated by Affinity Biosciences. Please choose the appropriate format for each application and consult Materials and Methods sections for additional details about the use of any product in these publications.

For Research Use Only.
Not for use in diagnostic or therapeutic procedures. Not for resale. Not for distribution without written consent. Affinity Biosciences will not be held responsible for patent infringement or other violations that may occur with the use of our products. Affinity Biosciences, Affinity Biosciences Logo and all other trademarks are the property of Affinity Biosciences LTD.