Serum Amyloid A Recombinant Rabbit mAb - #BF3487
製品説明
ソース:
Rabbit IgG
アプリケーション:
WB 1:1000-1:5000, IHC 1:100-1:200
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
*The optimal dilutions should be determined by the end user. For optimal experimental results, antibody reuse is not recommended.
*Tips:
WB: For western blot detection of denatured protein samples. IHC: For immunohistochemical detection of paraffin sections (IHC-p) or frozen sections (IHC-f) of tissue samples. IF/ICC: For immunofluorescence detection of cell samples. ELISA(peptide): For ELISA detection of antigenic peptide.
反応性:
Human
クローナリティ:
Monoclonal [ReFirm22934]
特異性:
Serum Amyloid A Recombinant Rabbit mAb detects endogenous levels of Serum Amyloid A.
コンジュゲート:
Unconjugated.
精製:
Affinity-chromatography.
保存:
Rabbit IgG in Tris-Glycine (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at -20 °C. Stable for 12 months from date of receipt.
別名:
折りたたみ／展開
SAA,PIG4,SAA2,TP53I4
免疫原
免疫原:
A synthetic peptide from human Serum Amyloid A
Uniprot:
遺伝子(ID):
発現特異性:
タンパク質の説明:
This gene encodes a member of the serum amyloid A family of apolipoproteins. The encoded preproprotein is proteolytically processed to generate the mature protein. This protein is a major acute phase protein that is highly expressed in response to inflammation and tissue injury. This protein also plays an important role in HDL metabolism and cholesterol homeostasis. High levels of this protein are associated with chronic inflammatory diseases including atherosclerosis,rheumatoid arthritis,Alzheimer's disease and Crohn's disease. This protein may also be a potential biomarker for certain tumors. Alternate splicing results in multiple transcript variants that encode the same protein. A pseudogene of this gene is found on chromosome 11.
タンパク質配列:
- P0DJI8 SAA1_HUMAN:
- Protein BLAST With
- NCBI/
- ExPASy/
- Uniprot
MKLLTGLVFCSLVLGVSSRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
研究背景
機能:
Major acute phase protein.
PTMs:
This protein is the precursor of amyloid protein A, which is formed by the removal of approximately 24 residues from the C-terminal end.
細胞の位置付け:
Secreted.
組織特異性:
Expressed by the liver; secreted in plasma (at protein level).
タンパク質ファミリー:
Belongs to the SAA family.
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For Research Use Only.
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